[HTML][HTML] On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles
ML Formica, DA Real, ML Picchio, E Catlin… - Applied Materials …, 2022 - Elsevier
The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …
Nanocrystals as a master key to deliver hydrophobic drugs via multiple administration routes
MB McGuckin, J Wang, R Ghanma, N Qin… - Journal of Controlled …, 2022 - Elsevier
The poor aqueous solubility of many approved drugs and most new chemical entities poses
a challenge to drug delivery scientists working in academic and industrial labs. Despite the …
a challenge to drug delivery scientists working in academic and industrial labs. Despite the …
Hydrogel-forming microarray patches with cyclodextrin drug reservoirs for long-acting delivery of poorly soluble cabotegravir sodium for HIV Pre-Exposure Prophylaxis
Hydrogel-forming microarray patches (HF-MAPs) offer minimally invasive, pain-free and
prolonged drug delivery. These devices are designed to be self-administered and self …
prolonged drug delivery. These devices are designed to be self-administered and self …
Ring inserts as a useful strategy to prepare tip-loaded microneedles for long-acting drug delivery with application in HIV pre-exposure prophylaxis
The role of microneedle array patches (MAPs) and, in particular, dissolving MAPs in
transdermal drug delivery has increased exponentially over the last decade. MAPs are able …
transdermal drug delivery has increased exponentially over the last decade. MAPs are able …
Microneedle‐assisted transdermal delivery of nanoparticles: Recent insights and prospects
AJ Guillot, M Martínez‐Navarrete… - Wiley …, 2023 - Wiley Online Library
Transdermal delivery of drugs offers an interesting alternative for the administration of
molecules that present certain troubles when delivered by the oral route. It can produce …
molecules that present certain troubles when delivered by the oral route. It can produce …
[HTML][HTML] Intradermal delivery of the antiretroviral drugs cabotegravir and rilpivirine by dissolving microarray patches: Investigation of lymphatic uptake
IK Ramöller, F Volpe-Zanutto, LK Vora… - Journal of Controlled …, 2024 - Elsevier
The lymphatic system possesses the main viral replication sites in the body following viral
infection. Unfortunately, current antiretroviral agents penetrate the lymph nodes insufficiently …
infection. Unfortunately, current antiretroviral agents penetrate the lymph nodes insufficiently …
[HTML][HTML] Bioadhesive eutectogels supporting drug nanocrystals for long-acting delivery to mucosal tissues
MB Bianchi, C Zhang, E Catlin, G Sandri, M Calderón… - Materials Today Bio, 2022 - Elsevier
Eutectogels (Egels) are an emerging class of soft ionic materials outperforming traditional
temperature-intolerant hydrogels and costly ionogels. Due to their excellent elasticity, non …
temperature-intolerant hydrogels and costly ionogels. Due to their excellent elasticity, non …
Application of multipolymers system in the development of hydrogel-forming microneedle integrated with polyethylene glycol reservoir for transdermal delivery of …
U Mahfufah, NAF Sultan, AMN Fitri, D Elim… - European Polymer …, 2023 - Elsevier
Parasitic infection is one of the health problems that cause many deaths in develo**
countries. One of the infectious parasites that is a problem for the world community is cystic …
countries. One of the infectious parasites that is a problem for the world community is cystic …
Polymeric microarray patches for enhanced transdermal delivery of the poorly soluble drug olanzapine
Transdermal drug delivery is an alternative route of administration that offers avoidance of
the associated drawbacks of orally and parenterally administered hydrophobics. However …
the associated drawbacks of orally and parenterally administered hydrophobics. However …
[HTML][HTML] Systemic delivery of tenofovir alafenamide using dissolving and implantable microneedle patches
The human immunodeficiency virus (HIV) remains a global health concern, with 37.7 million
people currently living with the infection and 1.5 million new cases every year. Current …
people currently living with the infection and 1.5 million new cases every year. Current …