Antibiotic adjuvants: a versatile approach to combat antibiotic resistance

G Dhanda, Y Acharya, J Haldar - ACS omega, 2023 - ACS Publications
The problem of antibiotic resistance is on the rise, with multidrug-resistant strains emerging
even to the last resort antibiotics. The drug discovery process is often stalled by stringent cut …

Supramolecular antibacterial materials for combatting antibiotic resistance

X Li, H Bai, Y Yang, J Yoon, S Wang… - Advanced …, 2019 - Wiley Online Library
Antibiotic‐resistant bacteria have emerged as a severe threat to human health. As effective
antibacterial therapies, supramolecular materials display unprecedented advantages …

Computer-aided drug design methods

W Yu, AD MacKerell - Antibiotics: methods and protocols, 2017 - Springer
Computational approaches are useful tools to interpret and guide experiments to expedite
the antibiotic drug design process. Structure-based drug design (SBDD) and ligand-based …

A 0D-2D heterojunction bismuth molybdate-anchored multifunctional hydrogel for highly efficient eradication of drug-resistant bacteria

X Wang, Q Li, Y Miao, X Chen, X Zhang, J Shi, F Liu… - ACS …, 2023 - ACS Publications
Due to the increasing antibiotic resistance and the lack of broad-spectrum antibiotics, there
is an urgent requirement to develop fresh strategies to combat multidrug-resistant …

[HTML][HTML] Novel 1, 2, 4-oxadiazole derivatives in drug discovery

K Biernacki, M Daśko, O Ciupak, K Kubiński, J Rachon… - Pharmaceuticals, 2020 - mdpi.com
Five-membered 1, 2, 4-oxadiazole heterocyclic ring has received considerable attention
because of its unique bioisosteric properties and an unusually wide spectrum of biological …

Eradicating Multidrug‐Resistant Bacteria Rapidly Using a Multi Functional g‐C3N4@ Bi2S3 Nanorod Heterojunction with or without Antibiotics

Y Li, X Liu, L Tan, Z Cui, D **g, X Yang… - Advanced Functional …, 2019 - Wiley Online Library
Wound infections caused by multidrug‐resistant (MDR) bacteria are hard to treat because of
tolerance to existing antibiotics, repeated infection, and concomitant inflammation. Herein …

Indole-based derivatives as potential antibacterial activity against methicillin-resistance Staphylococcus aureus (MRSA)

HL Qin, J Liu, WY Fang, L Ravindar… - European journal of …, 2020 - Elsevier
Antibacterial-resistance speaks to an overall alarm, particularly in regards to the flare-up of
methicillin-resistance Staphylococcus aureus (MRSA), a classic reason for genuine skin and …

Penicillin‐binding protein 2a of methicillin‐resistant Staphylococcus aureus

J Fishovitz, JA Hermoso, M Chang, S Mobashery - IUBMB life, 2014 - Wiley Online Library
High‐level resistance to β‐lactam antibiotics in methicillin‐resistant Staphylococcus aureus
(MRSA) is due to expression of penicillin‐binding protein 2a (PBP2a), a transpeptidase that …

Current promising strategies against antibiotic-resistant bacterial infections

J Ye, X Chen - Antibiotics, 2022 - mdpi.com
Infections caused by antibiotic-resistant bacteria (ARB) are one of the major global health
challenges of our time. In addition to develo** new antibiotics to combat ARB, sensitizing …

Molecular docking analysis and evaluation of the antimicrobial properties of the constituents of Geranium wallichianum D. Don ex Sweet from Kashmir Himalaya

WR Mir, BA Bhat, MA Rather, S Muzamil… - Scientific reports, 2022 - nature.com
Geranium wallichianum D. Don ex Sweet is a well-known medicinal plant in Kashmir
Himalya. The evidence for its modern medicinal applications remains majorly unexplored …