Systematic review and meta-analysis investigating moderators of long-term effects of exercise on cognition in healthy individuals

S Ludyga, M Gerber, U Pühse, VN Looser… - Nature human …, 2020 - nature.com
As cognitive function is linked with academic achievement, career success and mental
health, there is a need to understand how the cognitive benefits of long-term exercise can be …

Sex differences in hippocampal cognition and neurogenesis

S Yagi, LAM Galea - Neuropsychopharmacology, 2019 - nature.com
Sex differences are reported in hippocampal plasticity, cognition, and in a number of
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …

Comprehensive evaluation of the 5XFAD mouse model for preclinical testing applications: a MODEL-AD study

AL Oblak, PB Lin, KP Kotredes, RS Pandey… - Frontiers in aging …, 2021 - frontiersin.org
The ability to investigate therapeutic interventions in animal models of neurodegenerative
diseases depends on extensive characterization of the model (s) being used. There are …

Neurogenesis in aging and age-related neurodegenerative diseases

L Culig, X Chu, VA Bohr - Ageing research reviews, 2022 - Elsevier
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

The prevalence of Frascati-criteria-based HIV-associated neurocognitive disorder (HAND) in HIV-infected adults: a systematic review and meta-analysis

J Wei, J Hou, B Su, T Jiang, C Guo, W Wang… - Frontiers in …, 2020 - frontiersin.org
Background: The HIV associated mortality is decreasing in most countries due to the
widespread use of antiretroviral therapy. However, HIV-associated neurocognitive disorder …

Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease

DP Veitch, MW Weiner, PS Aisen… - Alzheimer's & …, 2022 - Wiley Online Library
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has
accumulated 15 years of clinical, neuroimaging, cognitive, biofluid biomarker and genetic …

Proportion of women and reporting of outcomes by sex in clinical trials for Alzheimer disease: a systematic review and meta-analysis

J Martinkova, FC Quevenco, H Karcher… - JAMA Network …, 2021 - jamanetwork.com
Importance Women represent two-thirds of patients with Alzheimer disease (AD), and sex
differences might affect results of randomized clinical trials (RCTs). However, little …

Sex differences in brain functional connectivity of hippocampus in mild cognitive impairment

J Williamson, A Yabluchanskiy, P Mukli… - Frontiers in aging …, 2022 - frontiersin.org
Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's Disease (AD). Prior
research shows that females are more impacted by MCI than males. On average females …

Sex and gender differences in cognitive resilience to aging and Alzheimer's disease

EM Arenaza‐Urquijo, R Boyle, K Casaletto… - Alzheimer's & …, 2024 - Wiley Online Library
Sex and gender—biological and social constructs—significantly impact the prevalence of
protective and risk factors, influencing the burden of Alzheimer's disease (AD; amyloid beta …

Female specific risk factors for the development of Alzheimer's disease neuropathology and cognitive impairment: Call for a precision medicine approach

C Udeh-Momoh, T Watermeyer - Ageing Research Reviews, 2021 - Elsevier
Alzheimer's disease (AD) includes a long asymptomatic stage, which precedes the formal
diagnosis of dementia. AD biomarker models provide a framework for precision medicine …