Meningococcal disease remains an important cause of morbidity and death worldwide
despite the development and increasing implementation of effective vaccines. Elimination of …

Bacterial uptake of DNA through type IV filaments is an essential component of natural
competence in numerous gram-positive and gram-negative species. Recent advances in the …

Since phages present a major challenge to survival in most environments, bacteria express
a battery of anti-phage defences including CRISPR–Cas, restriction-modification and …

We report here cryoelectron microscopy reconstructions of type IV pili (T4P) from two
important human pathogens, Pseudomonas aeruginosa and Neisseria gonorrhoeae, at∼ 8 …

Type IV pili (T4P) are bacterial appendages composed of protein subunits, called pilins,
noncovalently assembled into helical fibers. T4P are essential, in many bacterial species, for …

Acinetobacter baumannii is a Gram-negative coccobacillus found primarily in hospital
settings that has recently emerged as a source of hospital-acquired infections. A. baumannii …

Abstract Type 4 pili (T4P) are important virulence factors, which belong to a superfamily of
nanomachines ubiquitous in prokaryotes, called type 4 filaments (T4F). T4F are defined as …

Glycosylation is a co-and post-translational modification that is critical for the regulation of
the biophysical properties and biological activities of diverse proteins. Biosynthetic pathways …

ABSTRACT Type IV pilus (T4P)-like systems have been identified in almost every major
phylum of prokaryotic life. They include the type IVa pilus (T4aP), type II secretion system …

The current technique used for microbial identification in hospitals is matrix-assisted laser
desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). However, it suffers …