Radiomics improves cancer screening and early detection

RJ Gillies, MB Schabath - Cancer Epidemiology, Biomarkers & …, 2020 - aacrjournals.org
Imaging is a key technology in the early detection of cancers, including X-ray
mammography, low-dose CT for lung cancer, or optical imaging for skin, esophageal, or …

Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer

KM Wadosky, S Koochekpour - Oncotarget, 2016 - pmc.ncbi.nlm.nih.gov
Prostate cancer (PCa) is the most widely diagnosed male cancer in the Western World and
while low-and intermediate-risk PCa patients have a variety of treatment options, metastatic …

[HTML][HTML] Personalized medicine could transform healthcare

S Mathur, J Sutton - Biomedical reports, 2017 - spandidos-publications.com
Personalized medicine (PM) is about tailoring a treatment as individualized as the disease.
The approach relies on identifying genetic, epigenomic, and clinical information that allows …

Androgen receptor splice variants and prostate cancer: From bench to bedside

KM Wadosky, S Koochekpour - Oncotarget, 2017 - pmc.ncbi.nlm.nih.gov
Therapeutic interventions for advanced prostate cancer (PCa) center on inhibiting androgen
receptor (AR) and downstream signaling pathways. Resistance to androgen deprivation …

Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies

C Bajo-Santos, A Brokāne, P Zayakin… - Frontiers in molecular …, 2023 - frontiersin.org
Introduction: Extracellular vesicles (EVs) have emerged as a very attractive source of cancer-
derived RNA biomarkers for the early detection, prognosis and monitoring of various …

[HTML][HTML] Clinical relevance of circulating tumor cells in prostate cancer management

WA Cieślikowski, A Antczak, M Nowicki, M Zabel… - Biomedicines, 2021 - mdpi.com
Given the low specificity of the routinely used biomarker prostate-specific antigen, circulating
tumor cell (CTC) enumeration seems to be particularly useful in the monitoring of prostate …

Radical prostatectomy versus deferred treatment for localised prostate cancer

RWM Vernooij, M Lancee, A Cleves… - Cochrane Database …, 2020 - cochranelibrary.com
Background Prostate cancer is a common cancer but is oftentimes slow growing. When
confined to the prostate, radical prostatectomy (RP), which involves removal of the prostate …

Precision intervention for prostate cancer: re-evaluating who is at risk

A Papachristodoulou, C Abate-Shen - Cancer letters, 2022 - Elsevier
The vast majority of new prostate cancer diagnoses are low-grade tumors that are monitored
by active surveillance rather than undergoing immediate treatment. However, a subset of …

[HTML][HTML] Correlation between apparent diffusion coefficient value on diffusion-weighted MR imaging and Gleason score in prostate cancer

X Wu, P Reinikainen, A Vanhanen, M Kapanen… - Diagnostic and …, 2017 - Elsevier
Objectives To investigate whether diffusion-weighted imaging (DWI) apparent diffusion
coefficient (ADC) correlates with prostate cancer aggressiveness and further to compare the …

Could biparametric MRI replace multiparametric MRI in the management of prostate cancer?

R Iacob, ER Stoicescu, S Cerbu, DL Manolescu… - Life, 2023 - mdpi.com
Simple Summary Prostate cancer (PCa) is one of the most common types of tumors among
men, being potentially curable when diagnosed in early phases. With all this, this type of …