Myeloperoxidase as an active disease biomarker: recent biochemical and pathological perspectives

AA Khan, MA Alsahli, AH Rahmani - Medical sciences, 2018 - mdpi.com
Myeloperoxidase (MPO) belongs to the family of heme-containing peroxidases, produced
mostly from polymorphonuclear neutrophils. The active enzyme (150 kDa) is the product of …

Neutrophil lymphocyte ratio and cardiovascular disease risk: a systematic review and meta‐analysis

T Angkananard, T Anothaisintawee… - BioMed research …, 2018 - Wiley Online Library
Objective. This systematic review aimed to measure the association between neutrophil
lymphocyte ratio (NLR) and cardiovascular disease (CVD) risk. Methods. Relevant studies …

Anti-inflammatory treatment with colchicine in acute myocardial infarction: a pilot study

S Deftereos, G Giannopoulos, C Angelidis… - Circulation, 2015 - Am Heart Assoc
Background—Inflammatory processes have been identified as key mediators of the
deleterious effects of ischemia/reperfusion in ST-segment–elevation myocardial infarction …

Severity of psoriasis associates with aortic vascular inflammation detected by FDG PET/CT and neutrophil activation in a prospective observational study

HB Naik, B Natarajan, E Stansky… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—To understand whether directly measured psoriasis severity is associated with
vascular inflammation assessed by 18F-fluorodeoxyglucose positron emission tomography …

High neutrophil/lymphocyte ratio is associated with poor renal outcomes in Japanese patients with chronic kidney disease

R Yoshitomi, M Nakayama, T Sakoh, A Fukui… - Renal failure, 2019 - Taylor & Francis
Background: Several studies have shown that the neutrophil/lymphocyte ratio (NLR) is a
marker that reflects the state of systemic inflammation. A high NLR was reported to be …

Unexpected role of MPO-oxidized LDLs in atherosclerosis: In between inflammation and its resolution

C Tangeten, K Zouaoui Boudjeltia, C Delporte… - Antioxidants, 2022 - mdpi.com
Inflammation and its resolution are the result of the balance between pro-inflammatory and
pro-resolving factors, such as specialized pro-resolving mediators (SPMs). This balance is …

Association of interleukin-6 gene polymorphism with coronary artery disease: an updated systematic review and cumulative meta-analysis

H Hou, C Wang, F Sun, L Zhao, A Dun, Z Sun - Inflammation research, 2015 - Springer
Abstract Background Interleukin-6 (IL-6) is an important mediator of atherosclerotic disease
and is also associated with coronary artery disease (CAD). The growing evidences suggest …

Meconium proteins involved in iron metabolism

E Skarżyńska, A Jakimiuk, T Issat… - International Journal of …, 2024 - mdpi.com
The lack of specific biological materials and biomarkers limits our knowledge of the
mechanisms underlying intrauterine regulation of iron supply to the fetus. Determining the …

Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based …

RB Ruggeri, L Buckbinder, SW Bagley… - Journal of medicinal …, 2015 - ACS Publications
Myeloperoxidase (MPO) is a heme peroxidase that catalyzes the production of hypochlorous
acid. Clinical evidence suggests a causal role for MPO in various autoimmune and …

Renal toxicological evaluations of sulphonated nanocellulose from Khaya sengalensis seed in Wistar rats

A Adewuyi, CA Otuechere, OL Adebayo… - Chemico-biological …, 2018 - Elsevier
Nanocellulose is currently gaining attention due to its unique properties. This attention
includes its application as building blocks for develo** novel functional materials, plant …