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MAPK-activated protein kinases: servant or partner?
N Ronkina, M Gaestel - Annual review of biochemistry, 2022 - annualreviews.org
Mitogen-activated protein kinase (MAPK)-activated protein kinases (MAPKAPKs) are
defined by their exclusive activation by MAPKs. They can be activated by classical and …
defined by their exclusive activation by MAPKs. They can be activated by classical and …
Interleukin 33 is a guardian of barriers and a local alarmin
NT Martin, MU Martin - Nature immunology, 2016 - nature.com
Abstract Interleukin 33 (IL-33) is a member of the IL-1 family of cytokines with a growing
number of target cells and a plethora of biological functions. Although it has commonalities …
number of target cells and a plethora of biological functions. Although it has commonalities …
Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity
Mechanosensitive ion channels sense force and pressure in immune cells to drive the
inflammatory response in highly mechanical organs. Here, we report that Piezo1 channels …
inflammatory response in highly mechanical organs. Here, we report that Piezo1 channels …
A network map of IL-33 signaling pathway
Abstract Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that play a central
role in the regulation of immune responses. Its release from epithelial and endothelial cells …
role in the regulation of immune responses. Its release from epithelial and endothelial cells …
Conflicting vascular and metabolic impact of the IL-33/sST2 axis
Abstract Interleukin 33 (IL-33), which is expressed by several immune cell types, endothelial
and epithelial cells, and fibroblasts, is a cytokine of the IL-1 family that acts both intra-and …
and epithelial cells, and fibroblasts, is a cytokine of the IL-1 family that acts both intra-and …
The contrasting role of extracellular vesicles in vascular inflammation and tissue repair
S Oggero, S Austin-Williams, LV Norling - Frontiers in Pharmacology, 2019 - frontiersin.org
Extracellular vesicles are a heterogeneous family of vesicles, generated from different
subcellular compartments and released into the extracellular space. Composed of a lipid …
subcellular compartments and released into the extracellular space. Composed of a lipid …
Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations
Asthma is a complex disease with striking disparities across racial and ethnic groups.
Despite its relatively high burden, representation of individuals of African ancestry in asthma …
Despite its relatively high burden, representation of individuals of African ancestry in asthma …
[HTML][HTML] Dual immune regulatory roles of interleukin-33 in pathological conditions
H Guo, EA Bossila, X Ma, C Zhao, Y Zhao - Cells, 2022 - mdpi.com
Interleukin-33 (IL-33), a member of the IL-1 cytokine family and a multifunctional cytokine,
plays critical roles in maintaining host homeostasis and in pathological conditions, such as …
plays critical roles in maintaining host homeostasis and in pathological conditions, such as …
Pleiotropic Effects of IL-33 on CD4+ T Cell Differentiation and Effector Functions
IL-33, a member of the IL-1 family of cytokines, was originally described in 2005 as a
promoter of type 2 immune responses. However, recent evidence reveals a more complex …
promoter of type 2 immune responses. However, recent evidence reveals a more complex …
Peptide correlation analysis (PeCorA) reveals differential proteoform regulation
Shotgun proteomics techniques infer the presence and quantity of proteins using peptide
proxies produced by cleavage of the proteome with a protease. Most protein quantitation …
proxies produced by cleavage of the proteome with a protease. Most protein quantitation …