[HTML][HTML] Hippocampal GABAergic interneurons and memory
One of the most captivating questions in neuroscience revolves around the brain's ability to
efficiently and durably capture and store information. It must process continuous input from …
efficiently and durably capture and store information. It must process continuous input from …
An Integrated theory of false insights and beliefs under psychedelics
Psychedelics are recognised for their potential to re-orient beliefs. We propose a model of
how psychedelics can, in some cases, lead to false insights and thus false beliefs. We first …
how psychedelics can, in some cases, lead to false insights and thus false beliefs. We first …
Gamma oscillation plasticity is mediated via parvalbumin interneurons
Understanding the plasticity of neuronal networks is an emerging field of (patho-)
physiological research, yet the underlying cellular mechanisms remain poorly understood …
physiological research, yet the underlying cellular mechanisms remain poorly understood …
Gain control of sensory input across polysynaptic circuitries in mouse visual cortex by a single G protein-coupled receptor type (5-HT2A)
R Barzan, B Bozkurt, MM Nejad, ST Süß… - Nature …, 2024 - nature.com
Response gain is a crucial means by which modulatory systems control the impact of
sensory input. In the visual cortex, the serotonergic 5-HT2A receptor is key in such …
sensory input. In the visual cortex, the serotonergic 5-HT2A receptor is key in such …
Psilocybin and 2C-B at Encoding Distort Episodic Familiarity
Background As research on psychedelics (hallucinogenic serotonin receptor 2A agonists)
progresses, it is important to delineate the reliability of supposedly unique effects across this …
progresses, it is important to delineate the reliability of supposedly unique effects across this …
Thalamus mediates neocortical Down state transition via GABAB-receptor-targeting interneurons
Slow-wave sleep is characterized by near-synchronous alternation of active Up states and
quiescent Down states in the neocortex. Although the cortex itself can maintain these …
quiescent Down states in the neocortex. Although the cortex itself can maintain these …
Unique effects of sedatives, dissociatives, psychedelics, stimulants, and cannabinoids on episodic memory: A review and reanalysis of acute drug effects on …
Despite distinct classes of psychoactive drugs producing putatively unique states of
consciousness, there is surprising overlap in terms of their effects on episodic memory and …
consciousness, there is surprising overlap in terms of their effects on episodic memory and …
[HTML][HTML] Synthetic surprise as the foundation of the psychedelic experience
Psychedelic agents, such as LSD and psilocybin, induce marked alterations in
consciousness via activation of the 5-HT 2A receptor (5-HT 2A Rs). We hypothesize that …
consciousness via activation of the 5-HT 2A receptor (5-HT 2A Rs). We hypothesize that …
Kinetics and connectivity properties of parvalbumin-and somatostatin-positive inhibition in layer 2/3 medial entorhinal cortex
Abstract Parvalbumin-positive (Pvalb+) and somatostatin-positive (Sst+) cells are the two
largest subgroups of inhibitory interneurons. Studies in visual cortex indicate that synaptic …
largest subgroups of inhibitory interneurons. Studies in visual cortex indicate that synaptic …
Spontaneous persistent activity and inactivity in vivo reveals differential cortico-entorhinal functional connectivity
K Choudhary, S Berberich, TTG Hahn… - Nature …, 2024 - nature.com
Understanding the functional connectivity between brain regions and its emergent dynamics
is a central challenge. Here we present a theory-experiment hybrid approach involving …
is a central challenge. Here we present a theory-experiment hybrid approach involving …