Neurodegenerative disorders are accompanied by neuronal degeneration and glial
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …

Amyotrophic lateral sclerosis (ALS) is a fatal, severely debilitating and rapidly progressing
disorder affecting motor neurons in the brain, brainstem, and spinal cord. Unfortunately …

Insulin resistance as a hallmark of type 2 DM (T2DM) plays a role in dementia by promoting
pathological lesions or enhancing the vulnerability of the brain. Numerous studies related to …

Pain, one of the most important problems in the field of medicine and public health, has
great research significance. Opioids are still the main drugs to relieve pain now. However, its …

Insulin-like growth factor 1 receptor (IGF1R)-mediated signaling pathways modulate
important neurophysiological aspects in the central nervous system, including …

Insulin-like growth factor-I (IGF-I) exerts multiple actions, yet the role of IGF-I from different
sources is poorly understood. Here, we explored the functional and behavioral …

Aging is a physiological process accompanied by a decline in cognitive performance. The
cholinergic neurons of the basal forebrain provide projections to the cortex that are directly …

Throughout life, stress stimuli act upon the brain leading to morphological and functional
changes in advanced age, when it is likely to develop neurodegenerative disorders. There is …

Macrophage migration inhibitory factor (MIF) is a pro‐inflammatory cytokine that represents
a link between diet‐induced inflammation and insulin resistance. Our aim was to examine …

腰椎间盘源性神经痛免疫复合物表达及富血小板血浆的治疗机制 Page 1 Chinese Journal of
Tissue Engineering Research|Vol 27|No.18|June 2023|2935 **组织工程研究 Chinese …