GABAergic inhibition shapes the connectivity, activity and plasticity of the brain. A series of
exciting new discoveries provides compelling evidence that disruptions in a number of key …

Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental condition with a wide
spectrum of symptoms, mainly characterized by social, communication, and cognitive …

In this review, we discuss the significance of the synaptic excitation/inhibition (E/I) balance in
the context of homeostatic plasticity, whose primary goal is thought to maintain neuronal …

Perineuronal nets (PNN) are extracellular matrix (ECM) assemblies that preferentially
ensheath parvalbumin (PV) expressing interneurons. Converging evidence indicates that …

Abnormal sensory responses associated with Fragile X Syndrome (FXS) and autism
spectrum disorders include hypersensitivity and impaired habituation to repeated stimuli …

Functional neurological disorder (FND), formerly called conversion disorder, is a condition
characterized by neurological symptoms that lack an identifiable organic purpose. These …

Sensory hypersensitivity is a common symptom in autism spectrum disorders (ASDs),
including fragile X syndrome (FXS), and frequently leads to tactile defensiveness. In mouse …

Altered neurological sensory integration results in Sensory Processing Disorder (SPD), also
known as Sensory Regulation Dysfunction, Sensory Integration Dysfunction or Sensory …