Intestinal hypoxia and hypoxia-induced signalling as therapeutic targets for IBD

S Van Welden, AC Selfridge, P Hindryckx - … Reviews Gastroenterology & …, 2017 - nature.com
Tissue hypoxia occurs when local oxygen demand exceeds oxygen supply. In chronic
inflammatory conditions such as IBD, the increased oxygen demand by resident and gut …

Angiogenesis in inflammatory bowel disease

C Alkim, H Alkim, AR Koksal, S Boga… - International journal of …, 2015 - Wiley Online Library
Angiogenesis is an important component of pathogenesis of inflammatory bowel disease
(IBD). Chronic inflammation and angiogenesis are two closely related processes. Chronic …

Intestinal Anti-inflammatory Effects of Outer Membrane Vesicles from Escherichia coli Nissle 1917 in DSS-Experimental Colitis in Mice

MJ Fábrega, A Rodríguez-Nogales… - Frontiers in …, 2017 - frontiersin.org
Escherichia coli Nissle 1917 (EcN) is a probiotic strain with proven efficacy in inducing and
maintaining remission of ulcerative colitis. However, the microbial factors that mediate these …

[HTML][HTML] Role of the endothelium in inflammatory bowel diseases

WE Cromer, JM Mathis, DN Granger… - World journal of …, 2011 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBD) are a complex group of diseases involving alterations in
mucosal immunity and gastrointestinal physiology during both initiation and progressive …

Toxic megacolon

DM Autenrieth, DC Baumgart - Inflammatory bowel diseases, 2012 - academic.oup.com
Toxic megacolon represents a dreaded complication of mainly inflammatory or infectious
conditions of the colon. It is most commonly associated with inflammatory bowel disease …

Oat β-glucan ameliorates dextran sulfate sodium (DSS)-induced ulcerative colitis in mice

B Liu, Q Lin, T Yang, L Zeng, L Shi, Y Chen, F Luo - Food & function, 2015 - pubs.rsc.org
Ulcerative colitis is a major inflammatory bowel disease (IBD), characterized by inflammation
within the gastrointestinal tract through chronic or relapsing immune system activation. The …

Toxic megacolon: background, pathophysiology, management challenges and solutions

J Desai, M Elnaggar, AA Hanfy… - Clinical and experimental …, 2020 - Taylor & Francis
Toxic megacolon (TM) is one of the fatal complications of inflammatory bowel disease (IBD)
or any infectious etiology of the colon that is characterized by total or partial nonobstructive …

Pathogenic angiogenesis in IBD and experimental colitis: new ideas and therapeutic avenues

JH Chidlow Jr, D Shukla… - American Journal of …, 2007 - journals.physiology.org
Angiogenesis is now understood to play a major role in the pathology of chronic
inflammatory diseases and is indicated to exacerbate disease pathology. Recent evidence …

[HTML][HTML] Nitric oxide as a potential biomarker in inflammatory bowel disease

N Avdagić, A Zaćiragić, N Babić, M Hukić… - Bosnian journal of …, 2013 - ncbi.nlm.nih.gov
The aim of this study was to investigate changes in serum nitric oxide (NO) concentration in
inflammatory bowel diseases (IBD) patients and its use as potential biomarker in differential …

Current overview of extrinsic and intrinsic factors in etiology and progression of inflammatory bowel diseases

M Sobczak, A Fabisiak, N Murawska… - Pharmacological …, 2014 - Elsevier
Inflammatory bowel diseases (IBD) are chronic, relapsing disorders affecting gastrointestinal
(GI) tract and associated with intestinal mucosa damage and inflammation. The principal …