[HTML][HTML] Calcium and ROS: A mutual interplay

A Görlach, K Bertram, S Hudecova, O Krizanova - Redox biology, 2015 - Elsevier
Calcium is an important second messenger involved in intra-and extracellular signaling
cascades and plays an essential role in cell life and death decisions. The Ca 2+ signaling …

The role of calcium–calcineurin–NFAT signaling pathway in health and autoimmune diseases

YJ Park, SA Yoo, M Kim, WU Kim - Frontiers in immunology, 2020 - frontiersin.org
Calcium (Ca2+) is an essential signaling molecule that controls a wide range of biological
functions. In the immune system, calcium signals play a central role in a variety of cellular …

Calcium signalling and related ion channels in neutrophil recruitment and function

R Immler, SI Simon, M Sperandio - European journal of clinical …, 2018 - Wiley Online Library
The recruitment of neutrophils to sites of inflammation, their battle against invading
microorganisms through phagocytosis and the release of antimicrobial agents is a highly …

STING, the endoplasmic reticulum, and mitochondria: is three a crowd or a conversation?

JA Smith - Frontiers in immunology, 2021 - frontiersin.org
The anti-viral pattern recognition receptor STING and its partnering cytosolic DNA sensor
cGAS have been increasingly recognized to respond to self DNA in multiple pathologic …

New insights on the role of TRP channels in calcium signalling and immunomodulation: review of pathways and implications for clinical practice

S Froghi, CR Grant, R Tandon, A Quaglia… - Clinical reviews in …, 2021 - Springer
Calcium is the most abundant mineral in the human body and is central to many
physiological processes, including immune system activation and maintenance. Studies …

What is the evidence for the role of TRP channels in inflammatory and immune cells?

A Parenti, F De Logu, P Geppetti… - British journal of …, 2016 - Wiley Online Library
A complex network of many interacting mechanisms orchestrates immune and inflammatory
responses. Among these, the cation channels of the transient receptor potential (TRP) family …

TRPC Channels in the SOCE Scenario

JJ Lopez, I Jardin, J Sanchez-Collado, GM Salido… - Cells, 2020 - mdpi.com
Transient receptor potential (TRP) proteins form non-selective Ca2+ permeable channels
that contribute to the modulation of a number of physiological functions in a variety of cell …

Transient receptor potential channelopathies

B Nilius, G Owsianik - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
In the past years, several hereditary diseases caused by defects in transient receptor
potential channels (TRP) genes have been described. This review summarizes our current …

TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization

N Alessandri-Haber, OA Dina, X Chen… - Journal of …, 2009 - Soc Neuroscience
The transient receptor potential vanilloid 4 (TRPV4) contributes to mechanical hyperalgesia
of diverse etiologies, presumably as part of a mechanoreceptor signaling complex. To …

Calcium signaling and regulation of neutrophil functions: still a long way to go

J Hann, JL Bueb, F Tolle… - Journal of leukocyte …, 2020 - academic.oup.com
Neutrophils are the most abundant leukocytes in blood and disruption in their functions often
results in an increased risk of serious infections and inflammatory autoimmune diseases …