The emerging roles of sphingosine 1-phosphate and SphK1 in cancer resistance: a promising therapeutic target

SS Alkafaas, MI Elsalahaty, DF Ismail… - Cancer Cell …, 2024 - Springer
Cancer chemoresistance is a problematic dilemma that significantly restrains numerous
cancer management protocols. It can promote cancer recurrence, spreading of cancer, and …

Therapeutic Potential of Plant-Derived Compounds and Plant Extracts in Rheumatoid Arthritis—Comprehensive Review

M Kciuk, A Garg, M Rohilla, R Chaudhary, S Dhankhar… - Antioxidants, 2024 - mdpi.com
Rheumatoid arthritis (RA) is a persistent autoimmune disorder that is characterized by joint
inflammation, discomfort, and impairment. Despite the existence of several therapeutic …

Prospects of compounds of herbal plants as anticancer agents: a comprehensive review from molecular pathways

PC Situmorang, S Ilyas, SE Nugraha… - Frontiers in …, 2024 - frontiersin.org
Cancer refers to the proliferation and multiplication of aberrant cells inside the human body,
characterized by their capacity to proliferate and infiltrate various anatomical regions …

An Updated Review Summarizing the Anticancer Potential of Poly(Lactic‐co‐Glycolic Acid) (PLGA) Based Curcumin, Epigallocatechin Gallate, and Resveratrol …

P Pandey, M Verma, S Lakhanpal, S Pandey… - …, 2025 - Wiley Online Library
The utilization of nanoformulations derived from natural products for the treatment of many
human diseases, including cancer, is a rapidly develo** field. Conventional therapies …

[HTML][HTML] Potential Application of Plant-Derived Compounds in Multiple Sclerosis Management

S Woodfin, S Hall, A Ramerth, B Chapple, D Fausnacht… - Nutrients, 2024 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation,
demyelination, and neurodegeneration, resulting in significant disability and reduced quality …

[HTML][HTML] Epigallocatechin-3-gallate attenuates fluoride induced apoptosis via PI3K/FoxO1 pathway in ameloblast-like cells

Q Zhang, X Fei, Y Li, H Zhang, L Chen, J Ruan, N Dong - Toxicon, 2024 - Elsevier
Fluoride is a double-edged sword. It was widely used for early caries prevention while
excessive intake caused a toxicology effect, affected enamel development, and resulted in …

The interplay of mitochondrial dysfunction in oral diseases: Recent updates in pathogenesis and therapeutic implications

AHS Wadan, MA Ahmed, AH Ahmed, DES Ellakwa… - Mitochondrion, 2024 - Elsevier
Mitochondrial dysfunction is linked to various systemic and localized diseases, including
oral diseases like periodontitis, oral cancer, and temporomandibular joint disorders. This …

Therapeutic potential of flavonoids from traditional Chinese medicine in pancreatic cancer treatment

Q Wan, Q Ren, S Qiao, A Lyu, X He, F Li - Frontiers in Nutrition, 2024 - frontiersin.org
Pancreatic cancer (PC) is a highly aggressive malignancy with rising mortality rates globally.
Its diagnosis is often challenging due to its asymptomatic nature in the early stages …

Serving up health: How phytochemicals transform food into medicine in the battle against cancer

E Sharma, M Tewari, P Sati, I Sharma, DC Attri… - Food …, 2024 - Wiley Online Library
The escalating global cancer burden underscores the urgent need for more effective
therapeutic strategies. Phytochemicals, naturally occurring compounds in plants, have …

Epigallocatechin-3-gallate therapeutic potential in human diseases: molecular mechanisms and clinical studies

M Alam, M Gulzar, MS Akhtar, S Rashid, A Shamsi… - Molecular …, 2024 - Springer
Green tea has garnered increasing attention across age groups due to its numerous health
benefits, largely attributed to Epigallocatechin 3-gallate (EGCG), its key polyphenol. EGCG …