The coexistence of two pools of ATP synthase in mitochondria has been largely neglected
despite in vitro indications for the existence of reversible active/inactive state transitions in …

Mitochondria are metabolic hub, and act as primary sites for reactive oxygen species (ROS)
and metabolites generation. Mitochondrial Ca 2+ uptake contributes to Ca 2+ storage …

Mitochondrial ATP synthase (Complex V) catalyzes the last step of oxidative
phosphorylation and provides most of the energy (ATP) required by human cells. The …

While mechanisms controlling uncoupling protein-1 (UCP1) in thermogenic adipocytes play
a pivotal role in non-shivering thermogenesis, it remains unclear whether F1Fo-ATP …

Populus exhibits an extensive ecogeographical distribution throughout the Northern
Hemisphere, characterized by abundant interspecific hybrids. Specifically, P. tomentosa …

Mammalian F-ATP synthase is central to mitochondrial bioenergetics and is present in the
inner mitochondrial membrane in a dynamic oligomeric state of higher oligomers, tetramers …

The mitochondrial F1Fo‐ATP synthase uses a rotary mechanism to synthesise ATP. This
mechanism can, however, also operate in reverse, pum** protons at the expense of ATP …

Theragnostics is a promising approach that integrates diagnostics and therapeutics into a
single personalized strategy. To conduct effective theragnostic studies, it is essential to …

Trigonelline (TRIG) is a natural compound in an alkaloid family found in diverse plants. This
compound exerts anti-inflammatory, anti-allergic, anti-oxidative and anti-fibrotic activities in …

F1FO-ATP synthase is the mitochondrial complex responsible for ATP production. During
myocardial ischemia, it reverses its activity, hydrolyzing ATP and leading to energetic deficit …