An introduction to the endogenous cannabinoid system
The endocannabinoid system (ECS) is a widespread neuromodulatory system that plays
important roles in central nervous system development, synaptic plasticity, and the response …
important roles in central nervous system development, synaptic plasticity, and the response …
Endocannabinoid signalling in reward and addiction
LH Parsons, YL Hurd - Nature Reviews Neuroscience, 2015 - nature.com
Brain endocannabinoid (eCB) signalling influences the motivation for natural rewards (such
as palatable food, sexual activity and social interaction) and modulates the rewarding effects …
as palatable food, sexual activity and social interaction) and modulates the rewarding effects …
Modulation of striatal projection systems by dopamine
CR Gerfen, DJ Surmeier - Annual review of neuroscience, 2011 - annualreviews.org
The basal ganglia are a chain of subcortical nuclei that facilitate action selection. Two striatal
projection systems—so-called direct and indirect pathways—form the functional backbone of …
projection systems—so-called direct and indirect pathways—form the functional backbone of …
[HTML][HTML] Cannabis and its secondary metabolites: Their use as therapeutic drugs, toxicological aspects, and analytical determination
J Gonçalves, T Rosado, S Soares, AY Simão… - Medicines, 2019 - mdpi.com
Although the medicinal properties of Cannabis species have been known for centuries, the
interest on its main active secondary metabolites as therapeutic alternatives for several …
interest on its main active secondary metabolites as therapeutic alternatives for several …
The adolescent brain and age-related behavioral manifestations
LP Spear - Neuroscience & biobehavioral reviews, 2000 - Elsevier
To successfully negotiate the developmental transition between youth and adulthood,
adolescents must maneuver this often stressful period while acquiring skills necessary for …
adolescents must maneuver this often stressful period while acquiring skills necessary for …
Phosphatidylserine in the brain: metabolism and function
Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the
inner leaflet of the plasma membrane in neural tissues. PS is synthesized from …
inner leaflet of the plasma membrane in neural tissues. PS is synthesized from …
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
AC Howlett, F Barth, TI Bonner, G Cabral… - Pharmacological …, 2002 - Elsevier
Two types of cannabinoid receptor have been discovered so far, CB 1 (2.1: CBD: 1: CB1:),
cloned in 1990, and CB 2 (2.1: CBD: 2: CB2:), cloned in 1993. Distinction between these …
cloned in 1990, and CB 2 (2.1: CBD: 2: CB2:), cloned in 1993. Distinction between these …
Unconventional high-value products from microalgae: A review
Microalgae have gained significant importance in biotechnology development, providing
valuable goods and services in multiple applications. Although there is a rising market for …
valuable goods and services in multiple applications. Although there is a rising market for …
[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission
M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
The endocannabinoid system as an emerging target of pharmacotherapy
The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …
triggered an exponential growth of studies exploring the endocannabinoid system and its …