PARticular MARks: Histone ADP-ribosylation and the DNA damage response

C Özdemir, LR Purkey, A Sanchez, KM Miller - DNA repair, 2024‏ - Elsevier
Cellular and molecular responses to DNA damage are highly orchestrated and dynamic,
acting to preserve the maintenance and integrity of the genome. Histone proteins bind DNA …

[HTML][HTML] Targeting the DNA damage response (DDR) of cancer cells with natural compounds derived from Panax ginseng and other plants

SG Choi, M Shin, WY Kim - Journal of Ginseng Research, 2024‏ - Elsevier
DNA damage is a driver of cancer formation, leading to the impairment of repair
mechanisms in cancer cells and rendering them susceptible to DNA-damaging therapeutic …

[HTML][HTML] The Function of H2A Histone Variants and Their Roles in Diseases

X Yin, D Zeng, Y Liao, C Tang, Y Li - Biomolecules, 2024‏ - mdpi.com
Epigenetic regulation, which is characterized by reversible and heritable genetic alterations
without changing DNA sequences, has recently been increasingly studied in diseases …