Polycythemia vera: 2024 update on diagnosis, risk‐stratification, and management

A Tefferi, T Barbui - American journal of hematology, 2023 - Wiley Online Library
Abstract Disease Overview Polycythemia vera (PV) is a JAK2‐mutated myeloproliferative
neoplasm characterized by clonal erythrocytosis; other features include leukocytosis …

The international consensus classification of myeloid neoplasms and acute leukemias: myeloproliferative neoplasms

J Thiele, HM Kvasnicka, A Orazi… - American journal of …, 2023 - Wiley Online Library
A group of international experts, including hematopathologists, oncologists, and geneticists
were recently summoned (September 2021, Chicago, IL, USA) to update the 2016/17 World …

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data

DA Arber, A Orazi, RP Hasserjian… - Blood, The Journal …, 2022 - ashpublications.org
The classification of myeloid neoplasms and acute leukemias was last updated in 2016
within a collaboration between the World Health Organization (WHO), the Society for …

The RING finger protein family in health and disease

C Cai, YD Tang, J Zhai, C Zheng - Signal transduction and targeted …, 2022 - nature.com
Ubiquitination is a highly conserved and fundamental posttranslational modification (PTM) in
all eukaryotes regulating thousands of proteins. The RING (really interesting new gene) …

Molecular pathogenesis of the myeloproliferative neoplasms

G Greenfield, MF McMullin, K Mills - Journal of Hematology & Oncology, 2021 - Springer
The Philadelphia negative myeloproliferative neoplasms (MPN) compromise a
heterogeneous group of clonal myeloid stem cell disorders comprising polycythaemia vera …

[HTML][HTML] Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis

NB Leimkühler, HFE Gleitz, L Ronghui, IAM Snoeren… - Cell stem cell, 2021 - cell.com
Functional contributions of individual cellular components of the bone-marrow
microenvironment to myelofibrosis (MF) in patients with myeloproliferative neoplasms …

Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk‐stratification and management

A Tefferi, T Barbui - American journal of hematology, 2020 - Wiley Online Library
Disease overview Polycythemia vera (PV) and essential thrombocythemia (ET) are
myeloproliferative neoplasms (MPN) respectively characterized by clonal erythrocytosis and …

Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk‐stratification and management

A Tefferi, T Barbui - American journal of hematology, 2019 - Wiley Online Library
Abstract Disease Overview: Polycythemia vera (PV) and essential thrombocythemia (ET) are
myeloproliferative neoplasms respectively characterized by erythrocytosis and …

Primary myelofibrosis: 2021 update on diagnosis, risk‐stratification and management

A Tefferi - American journal of hematology, 2021 - Wiley Online Library
Abstract Disease Overview Primary myelofibrosis (PMF) is a myeloproliferative neoplasm
(MPN) characterized by stem cell‐derived clonal myeloproliferation that is often but not …

Challenges in the introduction of next-generation sequencing (NGS) for diagnostics of myeloid malignancies into clinical routine use

U Bacher, E Shumilov, J Flach, N Porret… - Blood cancer …, 2018 - nature.com
Given the vast phenotypic and genetic heterogeneity of acute and chronic myeloid
malignancies, hematologists have eagerly awaited the introduction of next-generation …