Adenoviral vector immunity: its implications and circumvention strategies

Y S. Ahi, D S. Bangari, S K. Mittal - Current gene therapy, 2011 - benthamdirect.com
Adenoviral (Ad) vectors have emerged as a promising gene delivery platform for a variety of
therapeutic and vaccine purposes during last two decades. However, the presence of …

Development of novel adenoviral vectors to overcome challenges observed with HAdV-5–based constructs

J Alonso-Padilla, T Papp, GL Kaján, M Benkő… - Molecular Therapy, 2016 - cell.com
Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been
extensively studied in preclinical models and clinical trials over the past two decades …

Marker vaccine strategies and candidate CSFV marker vaccines

XN Dong, YH Chen - Vaccine, 2007 - Elsevier
Classical swine fever (CSF) is an economically important highly contagious disease of
swine worldwide. Classical swine fever virus (CSFV) is its etiological agent, and the only …

Development of nonhuman adenoviruses as vaccine vectors

DS Bangari, SK Mittal - Vaccine, 2006 - Elsevier
Human adenoviral (HAd) vectors have demonstrated great potential as vaccine vectors.
Preclinical and clinical studies have demonstrated the feasibility of vector design, robust …

Cutaneous vaccination: the skin as an immunologically active tissue and the challenge of antigen delivery

S Babiuk, M Baca-Estrada, LA Babiuk, C Ewen… - Journal of Controlled …, 2000 - Elsevier
Vaccination is one of the major achievements of modern medicine. As a result of
vaccination, diseases such as polio and measles have been controlled and small pox has …

Current strategies and future directions for eluding adenoviral vector immunity

DS Bangari, SK Mittal - Current gene therapy, 2006 - ingentaconnect.com
Adenoviral (Ad) vectors can efficiently transduce a broad range of cell types and have been
used extensively in preclinical and clinical studies for gene delivery applications. The …

Detection of bovine and porcine adenoviruses for tracing the source of fecal contamination

C Maluquer de Motes… - Applied and …, 2004 - Am Soc Microbiol
In this study, a molecular procedure for the detection of adenoviruses of animal origin was
developed to evaluate the level of excretion of these viruses by swine and cattle and to …

Production of adenovirus vectors and their use as a delivery system for influenza vaccines

SV Vemula, SK Mittal - Expert opinion on biological therapy, 2010 - Taylor & Francis
Importance of the field: With the emergence of highly pathogenic avian influenza H5N1
viruses that have crossed species barriers and are responsible for lethal infections in …

An update on canine adenovirus type 2 and its vectors

T Bru, S Salinas, EJ Kremer - Viruses, 2010 - mdpi.com
Adenovirus vectors have significant potential for long-or short-term gene transfer. Preclinical
and clinical studies using human derived adenoviruses (HAd) have demonstrated the …

Circumventing antivector immunity: potential use of nonhuman adenoviral vectors

E Lopez-Gordo, II Podgorski, N Downes… - Human gene …, 2014 - liebertpub.com
Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide
variety of cell types and drive high-level transient transgene expression. While there have …