Present knowledge on peroxiredoxins is reviewed with special emphasis on catalytic
principles, specificities and biological function. Peroxiredoxins are low efficiency …

The intestinal parasite Entamoeba histolytica is one of the first protists for which a draft
genome sequence has been published. Although the genome is still incomplete, it is …

The relative amounts of ovothiol A (N1-methyl-4-mercaptohistidine) and trypanothione [N1,
N8-bis (glutathionyl) spermidine] have been determined in all life cycle stages of …

We report the cloning, expression and functional characterisation of a peroxidase belonging
to the peroxiredoxin family from the potato cyst nematode Globodera rostochiensis, the first …

Sulfur-containing amino acids play indispensable roles in a wide variety of biological
activities including protein synthesis, methylation, and biosynthesis of polyamines and …

Amebiasis is an intestinal infection widespread throughout the world caused by the human
pathogen Entamoeba histolytica. Metronidazole has been a drug of choice against …

Trypanosomes and Leishmania, the causative agents of severe tropical diseases, employ 2-
Cys-peroxiredoxins together with cysteine-homologues of glutathione peroxidases and …

Peroxiredoxins are an important class of antioxidant enzymes found from Archaea to
humans, which reduce and thereby detoxify peroxides and peroxynitrites. The major thiol …

Nowadays there are numerous pathogens that have created a resistance to commonly used
antibiotics and drugs. Therefore research is focused on finding new therapeutic targets and …

Amebiasis is a disease caused by the unicellular parasite Entamoeba histolytica. In most
cases, the infection is asymptomatic but when symptomatic, the infection can cause …