Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Biological imaging of chemical bonds by stimulated Raman scattering microscopy

F Hu, L Shi, W Min - Nature methods, 2019 - nature.com
All molecules consist of chemical bonds, and much can be learned from map** the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …

Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine

JX Cheng, XS **, M Lee, A Serrels, VG Brunton… - Chemical Society …, 2016 - pubs.rsc.org
Optical microscopy techniques have emerged as a cornerstone of biomedical research,
capable of probing the cellular functions of a vast range of substrates, whilst being minimally …

Coherent Raman scattering microscopy in biology and medicine

C Zhang, D Zhang, JX Cheng - Annual review of biomedical …, 2015 - annualreviews.org
Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free
visualization and analysis of functional, endogenous biomolecules in living systems. When …

Live-cell bioorthogonal chemical imaging: stimulated Raman scattering microscopy of vibrational probes

L Wei, F Hu, Z Chen, Y Shen, L Zhang… - Accounts of chemical …, 2016 - ACS Publications
Conspectus Innovations in light microscopy have tremendously revolutionized the way
researchers study biological systems with subcellular resolution. In particular, fluorescence …

Direct visualization of de novo lipogenesis in single living cells

J Li, JX Cheng - Scientific reports, 2014 - nature.com
Increased de novo lipogenesis is being increasingly recognized as a hallmark of cancer.
Despite recent advances in fluorescence microscopy, autoradiography and mass …

Raman imaging of small biomolecules

Y Shen, F Hu, W Min - Annual review of biophysics, 2019 - annualreviews.org
Imaging techniques greatly facilitate the comprehensive knowledge of biological systems.
Although imaging methodology for biomacromolecules such as protein and nucleic acids …

Review of stimulated Raman scattering microscopy techniques and applications in the biosciences

Y Li, B Shen, S Li, Y Zhao, J Qu, L Liu - Advanced Biology, 2021 - Wiley Online Library
Stimulated Raman scattering (SRS) microscopy is a nonlinear optical imaging method for
visualizing chemical content based on molecular vibrational bonds. Featuring high speed …