Bioinformatics applications on apache spark

R Guo, Y Zhao, Q Zou, X Fang, S Peng - GigaScience, 2018 - academic.oup.com
With the rapid development of next-generation sequencing technology, ever-increasing
quantities of genomic data pose a tremendous challenge to data processing. Therefore …

[HTML][HTML] Bioinformatics for NGS-based metagenomics and the application to biogas research

S Jünemann, N Kleinbölting, S Jaenicke, C Henke… - Journal of …, 2017 - Elsevier
Metagenomics has proven to be one of the most important research fields for microbial
ecology during the last decade. Starting from 16S rRNA marker gene analysis for the …

The shared antibiotic resistome of soil bacteria and human pathogens

KJ Forsberg, A Reyes, B Wang, EM Selleck… - science, 2012 - science.org
Soil microbiota represent one of the ancient evolutionary origins of antibiotic resistance and
have been proposed as a reservoir of resistance genes available for exchange with clinical …

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

G Zhao, T Vatanen, L Droit, A Park… - Proceedings of the …, 2017 - National Acad Sciences
Viruses have long been considered potential triggers of autoimmune diseases. Here we
defined the intestinal virome from birth to the development of autoimmunity in children at risk …

A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples

SN Naccache, S Federman, N Veeraraghavan… - Genome …, 2014 - genome.cshlp.org
Unbiased next-generation sequencing (NGS) approaches enable comprehensive pathogen
detection in the clinical microbiology laboratory and have numerous applications for public …

Gut DNA viromes of Malawian twins discordant for severe acute malnutrition

A Reyes, LV Blanton, S Cao, G Zhao… - Proceedings of the …, 2015 - National Acad Sciences
The bacterial component of the human gut microbiota undergoes a definable program of
postnatal development. Evidence is accumulating that this program is disrupted in children …

Ultrafast clustering algorithms for metagenomic sequence analysis

W Li, L Fu, B Niu, S Wu, J Wooley - Briefings in bioinformatics, 2012 - academic.oup.com
The rapid advances of high-throughput sequencing technologies dramatically prompted
metagenomic studies of microbial communities that exist at various environments …

WebMGA: a customizable web server for fast metagenomic sequence analysis

S Wu, Z Zhu, L Fu, B Niu, W Li - BMC genomics, 2011 - Springer
Background The new field of metagenomics studies microorganism communities by culture-
independent sequencing. With the advances in next-generation sequencing techniques …

Western and non-western gut microbiomes reveal new roles of Prevotella in carbohydrate metabolism and mouth–gut axis

V Prasoodanan PK, AK Sharma, S Mahajan… - npj Biofilms and …, 2021 - nature.com
The abundance and diversity of host-associated Prevotella species have a profound impact
on human health. To investigate the composition, diversity, and functional roles of Prevotella …

The unique composition of Indian gut microbiome, gene catalogue, and associated fecal metabolome deciphered using multi-omics approaches

DB Dhakan, A Maji, AK Sharma, R Saxena… - …, 2019 - academic.oup.com
Background Metagenomic studies carried out in the past decade have led to an enhanced
understanding of the gut microbiome in human health; however, the Indian gut microbiome …