Precise nanomedicine for intelligent therapy of cancer

H Chen, Z Gu, H An, C Chen, J Chen, R Cui… - Science China …, 2018‏ - Springer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

Hydrophobic interaction: a promising driving force for the biomedical applications of nucleic acids

F **ao, Z Chen, Z Wei, L Tian - Advanced Science, 2020‏ - Wiley Online Library
The comprehensive understanding and proper use of supramolecular interactions have
become critical for the development of functional materials, and so is the biomedical …

Recent advances in aptamer-based targeted drug delivery systems for cancer therapy

F Gao, J Yin, Y Chen, C Guo, H Hu… - Frontiers in bioengineering …, 2022‏ - frontiersin.org
The past decade has become an important strategy in precision medicine for the targeted
therapy of many diseases, expecially various types of cancer. As a promising targeted …

Rapid and ultra-sensitive lateral flow assay for pathogens based on multivalent aptamer and magnetic nanozyme

X Li, G Li, Q Pan, F Xue, Z Wang, C Peng - Biosensors and Bioelectronics, 2024‏ - Elsevier
Ultra-sensitive LFA methods for pathogen detection commonly depended on tedious and
time-consuming nucleic acid amplification. Here, a high affinity multivalent aptamer (multi …

Smart and functionalized development of nucleic acid‐based hydrogels: Assembly strategies, recent advances, and challenges

Y Zhang, L Zhu, J Tian, L Zhu, X Ma, X He… - Advanced …, 2021‏ - Wiley Online Library
Nucleic acid‐based hydrogels that integrate intrinsic biological properties of nucleic acids
and mechanical behavior of their advanced assemblies are appealing bioanalysis and …

Advances in the development of fluorescence probes for cell plasma membrane imaging

C Liu, X Gao, J Yuan, R Zhang - TrAC Trends in Analytical Chemistry, 2020‏ - Elsevier
Cell plasma membrane, the boundary between an individual live cell and its
microenvironment, plays important roles in cellular communication and signaling, and …

Redox-responsive molecularly imprinted nanoparticles for targeted intracellular delivery of protein toward cancer therapy

H Lu, S Xu, Z Guo, M Zhao, Z Liu - ACS nano, 2021‏ - ACS Publications
Although protein therapeutics is of significance in therapeutic intervention of cancers,
controlled delivery of therapeutic proteins still faces substantial challenges including …

Functional aptamer-embedded nanomaterials for diagnostics and therapeutics

S **e, L Ai, C Cui, T Fu, X Cheng, F Qu… - ACS applied materials & …, 2021‏ - ACS Publications
In the past decades, various nanomaterials with unique properties have been explored for
bioapplications. Meanwhile, aptamers, generated from the systematic evolution of ligands by …

DNA nanotechnology enters cell membranes

S Huo, H Li, AJ Boersma, A Herrmann - Advanced Science, 2019‏ - Wiley Online Library
DNA is more than a carrier of genetic information: It is a highly versatile structural motif for
the assembly of nanostructures, giving rise to a wide range of functionalities. In this regard …

Aptamer-engineered (nano) materials for theranostic applications

N Rabiee, S Chen, S Ahmadi, RN Veedu - Theranostics, 2023‏ - pmc.ncbi.nlm.nih.gov
A diverse array of organic and inorganic materials, including nanomaterials, has been
extensively employed in multifunctional biomedical applications. These applications …