INTRODUCTION The cerebral cortex, or neocortex, is critical to key mammalian skills such
as language, sociability, and sensorimotor control. This structure consists of dozens of …

Hemophagocytic lymphohistiocytosis (HLH) is characterized by immune dysregulation due
to inadequate restraint of overactivated immune cells and is associated with a variable …

This review highlights genes, proteins and subcellular mechanisms, recently shown to
influence cortical neuronal migration. A current view on mechanisms which become …

Aberrant activation or inhibition of potassium (K+) currents across the plasma membrane of
cells has been causally linked to altered neurotransmission, cardiac arrhythmias, endocrine …

Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3) is a member of a small
family of multifunctional cell surface-anchored glycoproteins functioning as co-receptors for …

Objective To determine the proportion of infant deaths occurring in the setting of a confirmed
genetic disorder. Study design A retrospective analysis of the electronic medical records of …

BACKGROUND AND PURPOSE: The “ears of the lynx” MR imaging sign has been
described in case reports of hereditary spastic paraplegia with a thin corpus callosum …

Histones mediate dynamic packaging of nuclear DNA in chromatin, a process that is
precisely controlled to guarantee efficient compaction of the genome and proper …

Sphingomyelinases generate ceramide from sphingomyelin as a second messenger in
intracellular signaling pathways involved in cell proliferation, differentiation, or apoptosis …

PRUNE is a member of the DHH (Asp-His-His) phosphoesterase protein superfamily of
molecules important for cell motility, and implicated in cancer progression. Here we …