[HTML][HTML] Pros and cons of ultra-high-field MRI/MRS for human application

ME Ladd, P Bachert, M Meyerspeer, E Moser… - Progress in nuclear …, 2018 - Elsevier
Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

MRI at 7 Tesla and above: demonstrated and potential capabilities

O Kraff, A Fischer, AM Nagel… - Journal of Magnetic …, 2015 - Wiley Online Library
With more than 40 installed MR systems worldwide operating at 7 Tesla or higher, ultra‐high‐
field (UHF) imaging has been established as a platform for clinically oriented research in …

31P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations

M Meyerspeer, C Boesch, D Cameron… - NMR in …, 2021 - Wiley Online Library
Skeletal muscle phosphorus‐31 31P MRS is the oldest MRS methodology to be applied to
in vivo metabolic research. The technical requirements of 31P MRS in skeletal muscle …

7 Tesla and beyond: advanced methods and clinical applications in magnetic resonance imaging

T Platt, ME Ladd, D Paech - Investigative radiology, 2021 - journals.lww.com
Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

7‐T MR—from research to clinical applications?

E Moser, F Stahlberg, ME Ladd… - NMR in …, 2012 - Wiley Online Library
Over 20 000 MR systems are currently installed worldwide and, although the majority
operate at magnetic fields of 1.5 T and below (ie about 70%), experience with 3‐T (in high …

[HTML][HTML] Assessing tissue metabolism by phosphorous-31 magnetic resonance spectroscopy and imaging: a methodology review

Y Liu, Y Gu, X Yu - Quantitative imaging in medicine and surgery, 2017 - ncbi.nlm.nih.gov
Many human diseases are caused by an imbalance between energy production and
demand. Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) …

[HTML][HTML] In-vivo 31P-MRS of skeletal muscle and liver: a way for non-invasive assessment of their metabolism

L Valkovič, M Chmelík, M Krššák - Analytical biochemistry, 2017 - Elsevier
In addition to direct assessment of high energy phosphorus containing metabolite content
within tissues, phosphorus magnetic resonance spectroscopy (31 P-MRS) provides options …

31P‐MRS of healthy human brain: ATP synthesis, metabolite concentrations, pH, and T1 relaxation times

J Ren, AD Sherry, CR Malloy - NMR in Biomedicine, 2015 - Wiley Online Library
The conventional method for measuring brain ATP synthesis is 31P saturation transfer (ST),
a technique typically dependent on prolonged pre‐saturation with γ‐ATP. In this study, ATP …

Human cardiac 31P magnetic resonance spectroscopy at 7 tesla

CT Rodgers, WT Clarke, C Snyder… - Magnetic resonance …, 2014 - Wiley Online Library
Purpose Phosphorus magnetic resonance spectroscopy (31P‐MRS) affords unique insight
into cardiac energetics but has a low intrinsic signal‐to‐noise ratio (SNR) in humans. Theory …

Magnetic resonance spectroscopy reveals mitochondrial dysfunction in amyotrophic lateral sclerosis

M Sassani, JJ Alix, CJ McDermott, K Baster, N Hoggard… - Brain, 2020 - academic.oup.com
Mitochondrial dysfunction is postulated to be central to amyotrophic lateral sclerosis (ALS)
pathophysiology. Evidence comes primarily from disease models and conclusive data to …