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Structural biology of HIV
BG Turner, MF Summers - Journal of molecular biology, 1999 - Elsevier
The human immunodeficiency virus (HIV) genome encodes a total of three structural
proteins, two envelope proteins, three enzymes, and six accessory proteins. Studies over the …
proteins, two envelope proteins, three enzymes, and six accessory proteins. Studies over the …
Structural determinants and mechanism of HIV-1 genome packaging
K Lu, X Heng, MF Summers - Journal of molecular biology, 2011 - Elsevier
Like all retroviruses, the human immunodeficiency virus selectively packages two copies of
its unspliced RNA genome, both of which are utilized for strand-transfer-mediated …
its unspliced RNA genome, both of which are utilized for strand-transfer-mediated …
Virus maturation by budding
H Garoff, R Hewson, DJE Opstelten - Microbiology and molecular …, 1998 - journals.asm.org
Enveloped viruses mature by budding at cellular membranes. It has been generally thought
that this process is driven by interactions between the viral transmembrane proteins and the …
that this process is driven by interactions between the viral transmembrane proteins and the …
RNA secondary structure and binding sites for gag gene products in the 5'packaging signal of human immunodeficiency virus type 1
J Clever, C Sassetti, TG Parslow - Journal of virology, 1995 - journals.asm.org
The selective encapsidation of retroviral RNA requires sequences in the Gag protein, as well
as a cis-acting RNA packaging signal (psi site) near the 5'end of the genomic transcript. Gag …
as a cis-acting RNA packaging signal (psi site) near the 5'end of the genomic transcript. Gag …
RNA packaging
R Berkowitz, J Fisher, SP Goff - Morphogenesis and maturation of …, 1996 - Springer
RNA Packaging Page 1 RNA Packaging R. BERKOWITZ 1, J. FISHER2, and SP GOFF2
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177 2 Packaging …
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177 2 Packaging …
Self-assembly in vitro of purified CA-NC proteins from Rous sarcoma virus and human immunodeficiency virus type 1
S Campbell, VM Vogt - Journal of virology, 1995 - journals.asm.org
The internal structural proteins of retroviruses are proteolytically processed from the Gag
polyprotein, which alone is able to assemble into virus-like particles when expressed in …
polyprotein, which alone is able to assemble into virus-like particles when expressed in …
Map** of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein
The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein contains two copies
of a sequence motif, the cysteine-histidine box, that is conserved among retroviruses. To …
of a sequence motif, the cysteine-histidine box, that is conserved among retroviruses. To …
The human immunodeficiency virus type 1 encapsidation site is a multipartite RNA element composed of functional hairpin structures
MS McBride, AT Panganiban - Journal of virology, 1996 - journals.asm.org
We analyzed the leader region of human immunodeficiency virus type 1 (HIV-1) RNA to
decipher the nature of the cis-acting E/psi element required for encapsidation of viral RNA …
decipher the nature of the cis-acting E/psi element required for encapsidation of viral RNA …
A 19-nucleotide sequence upstream of the 5'major splice donor is part of the dimerization domain of human immunodeficiency virus 1 genomic RNA
M Laughrea, L Jette - Biochemistry, 1994 - ACS Publications
Revised Manuscript Received August 24, 1994® abstract: The genome of all retroviruses,
including human immunodeficiency virus type 1 (HIV-1), consists of two identical RNAs …
including human immunodeficiency virus type 1 (HIV-1), consists of two identical RNAs …
Specific binding of HIV‐1 nucleocapsid protein to PSI RNA in vitro requires N‐terminal zinc finger and flanking basic amino acid residues.
J Dannull, A Surovoy, G Jung, K Moelling - The EMBO journal, 1994 - embopress.org
The nucleocapsid (NC) protein of human immunodeficiency virus HIV‐1 (NCp7) is
responsible for packaging the viral RNA by recognizing a packaging site (PSI) on the viral …
responsible for packaging the viral RNA by recognizing a packaging site (PSI) on the viral …