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Reanalysis suggests that genomic islands of speciation are due to reduced diversity, not reduced gene flow
The metaphor of 'genomic islands of speciation'was first used to describe heterogeneous
differentiation among loci between the genomes of closely related species. The biological …
differentiation among loci between the genomes of closely related species. The biological …
Adaptation from standing genetic variation
Populations adapt to novel environments in two distinct ways: selection on pre-existing
genetic variation and selection on new mutations. These alternative sources of beneficial …
genetic variation and selection on new mutations. These alternative sources of beneficial …
Selective sweeps
W Stephan - Genetics, 2019 - academic.oup.com
For almost 20 years, many inference methods have been developed to detect selective
sweeps and localize the targets of directional selection in the genome. These methods are …
sweeps and localize the targets of directional selection in the genome. These methods are …
Hitchhiking under positive Darwinian selection
Positive selection can be inferred from its effect on linked neutral variation. In the restrictive
case when there is no recombination, all linked variation is removed. If recombination is …
case when there is no recombination, all linked variation is removed. If recombination is …
Molecular signatures of natural selection
There is an increasing interest in detecting genes, or genomic regions, that have been
targeted by natural selection. The interest stems from a basic desire to learn more about …
targeted by natural selection. The interest stems from a basic desire to learn more about …
Detecting loci under selection in a hierarchically structured population
Patterns of genetic diversity between populations are often used to detect loci under
selection in genome scans. Indeed, loci involved in local adaptations should show high F ST …
selection in genome scans. Indeed, loci involved in local adaptations should show high F ST …
Interrogating a high-density SNP map for signatures of natural selection
Identifying genomic regions that have been targets of natural selection remains one of the
most important and challenging areas of research in genetics. To this end, we report an …
most important and challenging areas of research in genetics. To this end, we report an …
The coupling hypothesis: why genome scans may fail to map local adaptation genes
Genomic scans of multiple populations often reveal marker loci with greatly increased
differentiation between populations. Often this differentiation coincides in space with …
differentiation between populations. Often this differentiation coincides in space with …
Signals of recent positive selection in a worldwide sample of human populations
Genome-wide scans for recent positive selection in humans have yielded insight into the
mechanisms underlying the extensive phenotypic diversity in our species, but have focused …
mechanisms underlying the extensive phenotypic diversity in our species, but have focused …
Recombination rate variation and speciation: theoretical predictions and empirical results from rabbits and mice
Recently diverged taxa may continue to exchange genes. A number of models of speciation
with gene flow propose that the frequency of gene exchange will be lower in genomic …
with gene flow propose that the frequency of gene exchange will be lower in genomic …