Circulating microRNAs: a novel class of biomarkers to diagnose and monitor human cancers

K Zen, CY Zhang - Medicinal research reviews, 2012 - Wiley Online Library
Specific and sensitive non‐invasive biomarkers for the detection of human epithelial
malignancies are urgently required to reduce the worldwide morbidity and mortality caused …

Cancer molecular markers: A guide to cancer detection and management

M Nair, SS Sandhu, AK Sharma - Seminars in cancer biology, 2018 - Elsevier
Cancer is generally caused by the molecular alterations which lead to specific mutations.
Advances in molecular biology have provided an impetus to the study of cancers with …

microRNA: diagnostic perspective

O Faruq, A Vecchione - Frontiers in medicine, 2015 - frontiersin.org
Biomarkers are biological measures of a biological state. An ideal marker should be safe
and easy to measure, cost efficient, modifiable with treatment, and consistent across gender …

Aptamer-based colorimetric detection of proteins using a branched DNA cascade amplification strategy and unmodified gold nanoparticles

CC Chang, CY Chen, TL Chuang, TH Wu… - Biosensors and …, 2016 - Elsevier
A branched DNA amplification strategy was employed to design a colorimetric aptameric
biosensor using unmodified gold nanoparticles (AuNPs). First, a programmed DNA dendritic …

Circulating miRNA in atherosclerosis: a clinical biomarker and early diagnostic tool

AR Sharma, G Sharma, M Bhattacharya… - Current Molecular …, 2022 - benthamdirect.com
Atherosclerosis, a vascular disease, is characterized by narrowing the arteries and forming
plaque inside arteries. There is a record of 17.5 million associated deaths recorded …

Circulating microRNAs as a novel class of diagnostic biomarkers in gastrointestinal tumors detection: a meta-analysis based on 42 articles

R Wang, H Wen, Y Xu, Q Chen, Y Luo, Y Lin, Y Luo… - PloS one, 2014 - journals.plos.org
Objective MicroRNAs (miRNAs) have become the focus of most recent efforts in cancer
research. However, there have been inconsistencies in the literature regarding the suitability …

Simultaneous detection of VEGF and CEA by time-resolved chemiluminescence enzyme-linked aptamer assay

J Man, J Dong, Y Wang, L He, S Yu, F Yu… - International journal …, 2020 - Taylor & Francis
Background As two important tumor markers, vascular endothelial growth factor (VEGF) and
carcinoembryonic antigen (CEA) have a great value for clinical application in the early …

Diagnostic significance of miR-210 as a potential tumor biomarker of human cancer detection: an updated pooled analysis of 30 articles

S Feng, A He, D Wang, B Kang - OncoTargets and therapy, 2019 - Taylor & Francis
A large number of studies have explored the diagnostic value of miR-210 as a potential
diagnostic cancer biomarker to detect various cancers in patients. However, the results of its …

Clinical importance of DNA repair in sporadic colorectal cancer

GA Laporte, NM Leguisamo, AN Kalil, J Saffi - Critical reviews in oncology …, 2018 - Elsevier
Colorectal cancer (CRC) is the third major cause of cancer-related deaths worldwide.
However, despite the scientific efforts to provide a molecular classification to improve CRC …

Circulating MicroRNA as biomarkers: An update in prostate cancer

A Srivastava, S Suy, SP Collins… - Molecular and cellular …, 2011 - pmc.ncbi.nlm.nih.gov
Prostate cancer (PCa) is the most common non-skin cancer among men. Currently available
diagnostic tests for PCa are inadequate in terms of low specificity and poor sensitivity …