Affinity hydrogels for protein delivery

L Abune, Y Wang - Trends in pharmacological sciences, 2021 - cell.com
Proteins have been studied as therapeutic agents for treatment of various human diseases.
However, the delivery of protein drugs into the body is challenging. In this review, we …

[HTML][HTML] Engineered hydrogels for peripheral nerve repair

Y Liu, X Zhang, C **ao, B Liu - Materials Today Bio, 2023 - Elsevier
Peripheral nerve injury (PNI) is a complex disease that often appears in young adults. It is
characterized by a high incidence, limited treatment options, and poor clinical outcomes …

Injectable fibroblast growth factor-2 coacervate for persistent angiogenesis

H Chu, J Gao, CW Chen, J Huard… - Proceedings of the …, 2011 - National Acad Sciences
Enhancing the maturity of the newly formed blood vessels is critical for the success of
therapeutic angiogenesis. The maturation of vasculature relies on active participation of …

Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing

NR Johnson, Y Wang - Journal of Controlled Release, 2013 - Elsevier
Wound healing is a dynamic process that relies on coordinated signaling molecules to
succeed. Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) is …

Dual delivery of growth factors with coacervate-coated poly (lactic-co-glycolic acid) nanofiber improves neovascularization in a mouse skin flap model

MS Lee, T Ahmad, J Lee, HK Awada, Y Wang, K Kim… - Biomaterials, 2017 - Elsevier
Random skin flaps are commonly used in plastic and reconstructive surgery for patients
suffering from severe or large scale wounds or in facial reconstruction. However, skin flaps …

Polycations and their biomedical applications

K Kim, WCW Chen, Y Heo, Y Wang - Progress in Polymer Science, 2016 - Elsevier
Polycations are useful delivery vehicles for nucleic acids and proteins. Physicochemical
properties, safety, and cost are important design parameters for polycation-enabled …

Therapeutic angiogenesis: controlled delivery of angiogenic factors

H Chu, Y Wang - Therapeutic delivery, 2012 - Taylor & Francis
Therapeutic angiogenesis aims at treating ischemic diseases by generating new blood
vessels from existing vasculature. It relies on delivery of exogenous factors to stimulate …

Linear viscoelasticity of complex coacervates

Y Liu, HH Winter, SL Perry - Advances in colloid and interface science, 2017 - Elsevier
Rheology is a powerful method for material characterization that can provide detailed
information about the self-assembly, structure, and intermolecular interactions present in a …

Towards comprehensive cardiac repair and regeneration after myocardial infarction: Aspects to consider and proteins to deliver

HK Awada, MP Hwang, Y Wang - Biomaterials, 2016 - Elsevier
Ischemic heart disease is a leading cause of death worldwide. After the onset of myocardial
infarction, many pathological changes take place and progress the disease towards heart …

Mobilization of mesenchymal stem cells by stromal cell-derived factor-1 released from chitosan/tripolyphosphate/fucoidan nanoparticles

YC Huang, TJ Liu - Acta biomaterialia, 2012 - Elsevier
Stromal cell-derived factor 1 (SDF-1) is an important chemokine in stem cell mobilization,
and plays a critical role in the biological and physiological functions of mesenchymal stem …