Neutrophils are frontline cells of the innate immune system. These effector leukocytes are
equipped with intriguing antimicrobial machinery and consequently display high cytotoxic …

Neutrophils are indispensable antagonists of microbial infection and facilitators of wound
healing. In the cancer setting, a newfound appreciation for neutrophils has come into view …

The full neutrophil heterogeneity and differentiation landscape remains incompletely
characterized. Here, we profiled> 25,000 differentiating and mature mouse neutrophils using …

Phagocytes form a family of immune cells that play a crucial role in tissue maintenance and
help orchestrate the immune response. This family of cells can be separated by their nuclear …

Chemokines are chemotactic cytokines that control the migration and positioning of immune
cells in tissues and are critical for the function of the innate immune system. Chemokines …

Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …

Unique among leukocytes, neutrophils follow daily cycles of release from and migration
back into the bone marrow, where they are eliminated. Because removal of dying cells …

Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

The circadian system is an important regulator of immune function. Human inflammatory
lung diseases frequently show time-of-day variation in symptom severity and lung function …

The phagocytic clearance of dying cells in a tissue is a highly orchestrated series of
intercellular events coordinated by a complex signaling network. Recent data from genetic …