Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …
rising, as younger age mortality declines. However, the age-specific incidence of dementia …
Arterial hypertension
Arterial hypertension is the most important contributor to the global burden of disease;
however, disease control remains poor. Although the diagnosis of hypertension is still based …
however, disease control remains poor. Although the diagnosis of hypertension is still based …
Association of systolic blood pressure with dementia risk and the role of age, U-shaped associations, and mortality
Importance The optimal systolic blood pressure (SBP) to minimize the risk of dementia in
older age is unknown. Objective To investigate whether the association between SBP and …
older age is unknown. Objective To investigate whether the association between SBP and …
[HTML][HTML] Promoting successful cognitive aging: a ten-year update
A decade has passed since we published a comprehensive review in this journal
addressing the topic of promoting successful cognitive aging, making this a good time to …
addressing the topic of promoting successful cognitive aging, making this a good time to …
Shared risk factors between dementia and atherosclerotic cardiovascular disease
LT Nordestgaard, M Christoffersen… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease is the most common form of dementia, and the prodromal phases of
Alzheimer's disease can last for decades. Vascular dementia is the second most common …
Alzheimer's disease can last for decades. Vascular dementia is the second most common …
A roadmap to build a phenotypic metric of ageing: insights from the Baltimore Longitudinal Study of Aging
Over the past three decades, considerable effort has been dedicated to quantifying the pace
of ageing yet identifying the most essential metrics of ageing remains challenging due to …
of ageing yet identifying the most essential metrics of ageing remains challenging due to …
How much lowering of blood pressure is required to prevent cardiovascular disease in patients with and without previous cardiovascular disease?
Abstract Purpose of Review To review the recent large-scale randomised evidence on
pharmacologic reduction in blood pressure for the primary and secondary prevention of …
pharmacologic reduction in blood pressure for the primary and secondary prevention of …
[HTML][HTML] Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an …
Background The effects of pharmacological blood-pressure-lowering on cardiovascular
outcomes in individuals aged 70 years and older, particularly when blood pressure is not …
outcomes in individuals aged 70 years and older, particularly when blood pressure is not …
Blood pressure in frail older adults: associations with cardiovascular outcomes and all-cause mortality
Background Blood pressure (BP) management in frail older people is challenging. An
randomised controlled trial of largely non-frail older people found cardiovascular and …
randomised controlled trial of largely non-frail older people found cardiovascular and …
Age of hypertension onset: overview of research and how to apply in practice
Abstract Purpose of Review To review the current evidence on research related to age of
hypertension onset—its definition, correlates, heritability, and association with adverse …
hypertension onset—its definition, correlates, heritability, and association with adverse …