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Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology
CA Brosey, JA Tainer - Current opinion in structural biology, 2019 - Elsevier
Highlights•SAXS captures architecture and dynamics to elucidate molecular
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …
Cryo-soft X-ray tomography: using soft X-rays to explore the ultrastructure of whole cells
Cryo-soft X-ray tomography is an imaging technique that addresses the need for mesoscale
imaging of cellular ultrastructure of relatively thick samples without the need for staining or …
imaging of cellular ultrastructure of relatively thick samples without the need for staining or …
Nuclear and cytoplasmic spatial protein quality control is coordinated by nuclear–vacuolar junctions and perinuclear ESCRT
Effective protein quality control (PQC), essential for cellular health, relies on spatial
sequestration of misfolded proteins into defined inclusions. Here we reveal the coordination …
sequestration of misfolded proteins into defined inclusions. Here we reveal the coordination …
Three-dimensional label-free observing of the self-assembled nanoparticles inside a single cell at nanoscale resolution
H Zhou, Y Guo, T Fu, Y Peng, Z Chen, Y Cui, M Guo… - ACS …, 2024 - ACS Publications
Understanding the intracellular behavior of nanoparticles (NPs) plays a key role in
optimizing the self-assembly performance of nanomedicine. However, conducting the 3D …
optimizing the self-assembly performance of nanomedicine. However, conducting the 3D …
[HTML][HTML] Opportunities and challenges in building a spatiotemporal multi-scale model of the human pancreatic β cell
The construction of a predictive model of an entire eukaryotic cell that describes its dynamic
structure from atomic to cellular scales is a grand challenge at the intersection of biology …
structure from atomic to cellular scales is a grand challenge at the intersection of biology …
Advanced light source analytical techniques for exploring the biological behavior and fate of nanomedicines
M Cao, K Zhang, S Zhang, Y Wang… - ACS Central Science, 2022 - ACS Publications
Exploration of the biological behavior and fate of nanoparticles, as affected by the
nanomaterial–biology (nano–bio) interaction, has become progressively critical for guiding …
nanomaterial–biology (nano–bio) interaction, has become progressively critical for guiding …