Hygiene hypothesis and autoimmune diseases: A narrative review of clinical evidences and mechanisms

G Murdaca, M Greco, M Borro, S Gangemi - Autoimmunity Reviews, 2021 - Elsevier
Since the start of the “modern era”, characterized by the increase in urbanization, a
progressive attention to hygiene and autoimmune conditions has considerably grown …

Genetic, environmental and lifestyle determinants of accelerated telomere attrition as contributors to risk and severity of multiple sclerosis

M Hecker, J Bühring, B Fitzner, PS Rommer, UK Zettl - Biomolecules, 2021 - mdpi.com
Telomeres are protective structures at the ends of linear chromosomes. Shortened telomere
lengths (TL) are an indicator of premature biological aging and have been associated with a …

Helicobacter pylori infection and risk of multiple sclerosis: An updated meta‐analysis

D Arjmandi, A Abdollahi, A Ardekani, I Razavian… - …, 2022 - Wiley Online Library
Background There is considerable controversy around the question as to whether
Helicobacter pylori (H. pylori) infection has a protective or causative role in the development …

[HTML][HTML] Diagnostic approach to Helicobacter pylori-related gastric oncogenesis

S Rupp, A Papaefthymiou, E Chatzimichael… - Annals of …, 2022 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is a causative agent of peptic ulcer disease and plays an
important role in the development of various other upper and lower gastrointestinal tract and …

The trimebutine effect on Helicobacter pylori-related gastrointestinal tract and brain disorders: A hypothesis

M Boziki, N Grigoriadis, A Papaefthymiou… - Neurochemistry …, 2021 - Elsevier
The localization of bacterial components and/or metabolites in the central nervous system
may elicit neuroinflammation and/or neurodegeneration. Helicobacter pylori (a non …

Impact of Helicobacter pylori and metabolic syndrome on mast cell activation-related pathophysiology and neurodegeneration

J Kountouras, M Boziki, E Kazakos, P Theotokis… - Neurochemistry …, 2024 - Elsevier
Both Helicobacter pylori (H. pylori) infection and metabolic syndrome (MetS) are highly
prevalent worldwide. The emergence of relevant research suggesting a pathogenic linkage …

[HTML][HTML] Impact of Mast Cell Activation on Neurodegeneration: A Potential Role for Gut–Brain Axis and Helicobacter pylori Infection

M Boziki, P Theotokis, E Kesidou, M Nella… - Neurology …, 2024 - mdpi.com
Background: The innate immune response aims to prevent pathogens from entering the
organism and/or to facilitate pathogen clearance. Innate immune cells, such as …

Impact of Helicobacter pylori‐related metabolic syndrome with hyperhomocysteinemia on extragastric pathologies.

J Kountouras, M Doulberis… - Journal of …, 2022 - search.ebscohost.com
Specifically, cognitively normal elderly persons with high A have hyperhomocysteinemia,
thinner temporal lobe, and lesser daily memory. 14 Our own results indicate that active I Hp …

2‐Mercapto Benzoxazole Derivatives as Novel Leads: Urease Inhibition, In Vitro and In Silico Studies

MM Balogun, S Shamim, KM Khan, U Salar… - …, 2021 - Wiley Online Library
Twenty‐three benzoxazole derivatives were prepared through two‐step reaction strategy.
The precursor, 2‐mercapto benzoxazole was synthesized by reacting 2‐amino phenol with …

[HTML][HTML] Serum Evaluation of Helicobacter pylori in Patients with Multiple Sclerosis

M Meshkat, Y Behjati, M Bakhshi, Z Meshkat… - Archives of …, 2023 - brieflands.com
Background: Multiple sclerosis (MS) is an autoimmune inflammatory disorder of the central
nervous system of unknown etiology, which is believed to be caused by immune …