Autosomal recessive primary microcephaly (MCPH) is a neurodevelopmental disorder that
is characterised by microcephaly present at birth and non-progressive mental retardation …

The relatively large brain and expanded cerebral cortex of humans is unusual in the animal
kingdom and is thought to have promoted our adaptability and success as a species. One …

Serine/arginine-rich splicing factor 2 (SRSF2) is an RNA-binding protein that plays important
roles in splicing of mRNA precursors. SRSF2 mutations are frequently found in patients with …

Autosomal recessive primary microcephaly (MCPH), historically referred to as Microcephalia
vera, is a genetically and clinically heterogeneous disease. Patients with MCPH typically …

Abstract Autosomal Recessive Primary Microcephaly (MCPH) is a rare disorder of
neurogenic mitosis characterized by reduced head circumference at birth with variable …

Autosomal recessive primary microcephaly (MCPH) is a rare hereditary
neurodevelopmental disorder characterized by a marked reduction in brain size and …

Autosomal recessive primary microcephaly (MCPH) is characterized by small brain size as a
result of deficient neuron production in the develo** cerebral cortex. Although MCPH is a …

Centrosome forms the backbone of cell cycle progression mechanism. Recent debates have
occurred regarding the essentiality of centrosome in cell cycle regulation. CEP family protein …

Colorectal carcinogenesis and progression are associated with aberrant alternative splicing,
yet its molecular mechanisms remain largely unexplored. Here, we find that Microrchidia …

The centrosome, consisting of centrioles and the associated pericentriolar material, is the
main microtubule-organizing centre (MTOC) in animal cells. During most of interphase, the …