Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non–small-cell lung cancer

A Aupérin, C Le Péchoux, E Rolland… - Journal of clinical …, 2010‏ - ascopubs.org
Purpose The previous individual patient data meta-analyses of chemotherapy in locally
advanced non–small-cell lung cancer (NSCLC) showed that adding sequential or …

Multidisciplinary management of lung cancer

A Spira, DS Ettinger - New England Journal of Medicine, 2004‏ - Mass Medical Soc
Despite years of research, the five-year survival rate among patients with lung cancer is a
mere 14 percent. Lung cancer is divided into two major types—non–small-cell lung cancer …

Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial

KS Albain, RS Swann, VW Rusch, AT Turrisi… - The Lancet, 2009‏ - thelancet.com
Background Results from phase II studies in patients with stage IIIA non-small-cell lung
cancer with ipsilateral mediastinal nodal metastases (N2) have shown the feasibility of …

Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non–small-cell lung cancer …

K Kelly, K Chansky, LE Gaspar, KS Albain… - Journal of clinical …, 2008‏ - ascopubs.org
Purpose Early clinical studies with gefitinib showed promising efficacy and mild toxicity in
patients with advanced non–small-cell lung cancer (NSCLC). Thus, gefitinib was an ideal …

Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage III non–small-cell lung …

N Hanna, M Neubauer, C Yiannoutsos… - Journal of clinical …, 2008‏ - ascopubs.org
Purpose Concurrent chemoradiotherapy is standard treatment for patients with inoperable
stage III non–small-cell lung cancer (NSCLC). A phase II study by the Southwest Oncology …

Induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for regionally advanced unresectable stage III non–small-cell lung …

EE Vokes, JE Herndon, MJ Kelley… - Journal of clinical …, 2007‏ - ascopubs.org
Purpose Standard therapy for unresectable stage III non–small-cell lung cancer includes
concomitant chemoradiotherapy. In Cancer and Leukemia Group B 39801, we evaluated …

Concurrent chemoradiotherapy in non‐small cell lung cancer

N O'Rourke, MR i Figuls, NF Bernadó… - Cochrane Database …, 2010‏ - cochranelibrary.com
Background This is an updated version of the original review published in Issue 4, 2004.
The use of concurrent chemotherapy and radiotherapy in non‐small cell lung cancer …

Advances in radiotherapy and implications for the next century: a historical perspective

PP Connell, S Hellman - Cancer research, 2009‏ - AACR
The use of ionizing radiation for the treatment of cancer dates back to the late 19th century,
remarkably soon after Roentgen described X-rays in 1895 and the use of brachytherapy …

Randomized phase III trial of sequential chemoradiotherapy compared with concurrent chemoradiotherapy in locally advanced non–small-cell lung cancer: Groupe …

P Fournel, G Robinet, P Thomas, PJ Souquet… - Journal of clinical …, 2005‏ - ascopubs.org
Purpose We conducted a phase III study to compare the survival impact of concurrent versus
sequential treatment with radiotherapy (RT) and chemotherapy (CT) in unresectable stage III …

Higher biologically effective dose of radiotherapy is associated with improved outcomes for locally advanced non–small cell lung carcinoma treated with …

M Machtay, K Bae, B Movsas, R Paulus… - International Journal of …, 2012‏ - Elsevier
PURPOSE: Patients treated with chemoradiotherapy for locally advanced non–small-cell
lung carcinoma (LA-NSCLC) were analyzed for local-regional failure (LRF) and overall …