Anticancer mechanism of coumarin-based derivatives

AK Yadav, RM Shrestha, PN Yadav - European Journal of Medicinal …, 2024 - Elsevier
The structural motif of coumarins is related with various biological activities and
pharmacological properties. Both natural coumarin extracted from various plants or a new …

Coumarin-transition metal complexes with biological activity: current trends and perspectives

LT Todorov, IP Kostova - Frontiers in Chemistry, 2024 - frontiersin.org
Coumarin (2H-1-benzopyran-2-one) presents the fundamental structure of an enormous
class of biologically active compounds of natural, semi-synthetic, and synthetic origin …

Synthesis of 7, 8-dihydroxy-4-phenylbenzo [g] coumarins as potential multitarget anti-skin-aging candidates

YF Mustafa - Journal of Molecular Structure, 2025 - Elsevier
Skin aging is a gradual, spontaneous, slow-processing, and natural phenomenon that
induces a negative impact on the skin's function and structure. Numerous cosmoceutical …

[HTML][HTML] Synthesis, characterization, anticancer activity, molecular docking and DFT calculation of 3-acetylcoumarin thiosemicarbazones and Schiff's bases

AK Yadav, N Singh, M Silwal, A Adhikari, PN Yadav - Results in Chemistry, 2024 - Elsevier
The new thiosemicarbazones (3a-d) of 3-acetylumbelliferone and Schiff's bases (4a-b) of 3-
acetylcoumarin were synthesized, characterized by elemental analysis, UV–Vis, FT-IR …

Novel Mononuclear Cu (II), Ni (II), and Co (II) Complexes of Coumarinyl‐Pyrazolyl‐Thiazole Thiosemicarbazone: Synthesis, Characterization, and Biological …

M Shebl, TE Ali, MA Assiri - Applied Organometallic Chemistry, 2025 - Wiley Online Library
ABSTRACT Cu (II), Ni (II), and Co (II) acetates reacted with a thiosemicarbazone ligand
(CPPTSC; HL) to produce novel solid complexes with the general formula [M (L)(H2O) m] …

[PDF][PDF] Hybrid Organic-Inorganic Copper and Cobalt Complexes for Antimicrobial Potential Applications

SS Al-Jameel, IM Ababutain… - Cell Physiol …, 2024 - cellphysiolbiochem.com
Abstract Background/Aims: The naturally occurring phenolic chemical curcumin (CUR),
which was derived from the Curcuma longa plant, has a variety of biological actions …

Synthesis, characterization, and anticancer potency of coumarin-derived thiosemicarbazones and their Copper (II) complexes

RM Shrestha, K Mahiya, A Shrestha… - Inorganic Chemistry …, 2024 - Elsevier
A series of 3-acetylcoumarin-based thiosemicarbazones and their copper (II) complexes
were synthesized and characterized by elemental analysis, IR, UV–Vis, HR-ESI Mass, NMR …

Coumarin based Schiff base proligands as promising antioxidant, antibacterial and anticancer agents: DFT and molecular docking correlations

A Santu, E Manoj - Journal of Molecular Structure, 2025 - Elsevier
In drug development, coumarin scaffolds are widely used to treat various illnesses, including
cancer. The biological potentials of Schiff base compounds derived from 3-acetyl coumarin …

Potent drug candidature of copper-coordinated metallodrug: Experimental study, spectroscopic insights, anticancer activity, apoptosis analysis, cell cycle, theoretical …

R Fouad, TE Ali, MA Assiri, AAM Ali - Inorganic Chemistry Communications, 2024 - Elsevier
The biological properties of the thiocarbohydrazone, pyrazole, and copper ions are well-
known, thus copper complexes incorporated with pyrazole-thiocarbohydrazone hybrid …

The current landscape of coumarin hybrids with antibreast cancer therapeutic applications: An updated review

R Wang, Z Chen, Y Huang, Q Zhang… - Archiv der …, 2024 - Wiley Online Library
Globally, breast cancer (BC) has the highest prevalence among malignant diseases. BC is
also the primary cause of death among women. Notably, BC morbidity has been increasing …