Oxidation of drugs during drug product development: problems and solutions
A Gabrič, Ž Hodnik, S Pajk - Pharmaceutics, 2022 - mdpi.com
Oxidation is the second most common degradation pathway for pharmaceuticals, after
hydrolysis. However, in contrast to hydrolysis, oxidation is mechanistically more complex …
hydrolysis. However, in contrast to hydrolysis, oxidation is mechanistically more complex …
Analysis and removal of pharmaceutical residues from wastewater using membrane bioreactors: a review
C Femina Carolin, P Senthil Kumar… - Environmental …, 2021 - Springer
Pharmaceutical compounds such antibiotics, anti-inflammatories, psychotropics, human
drugs, hormones, anticonvulsants, antidepressants, veterinary drugs and steroids occur …
drugs, hormones, anticonvulsants, antidepressants, veterinary drugs and steroids occur …
Application of advanced environmentally benign assessment tools in determining ternary cardiovascular drug combination by RP-HPLC with analytical quality by …
Assessing any analytical method is becoming an important aspect for showcasing its
importance and impact on the environment. The present work aimed to showcase different …
importance and impact on the environment. The present work aimed to showcase different …
Integrative AQbD, up-to-date greenness, and whiteness tools for evaluation of a sustainable RP-HPLC method used for simultaneous separation of triple …
The present study was designed to develop and validate a simple and fast RP-HPLC
method for simultaneously evaluating hydrochlorothiazide (HCTZ), amlodipine besylate …
method for simultaneously evaluating hydrochlorothiazide (HCTZ), amlodipine besylate …
Talc concentration effect on shelf life of acetaminophen tablets
Excipients in pharmaceutical formulations are inactive ingredient from the biological point of
view, but they have a key role in the preparation, and they can alter the stability of the active …
view, but they have a key role in the preparation, and they can alter the stability of the active …
[HTML][HTML] Theoretical and experimental model of molecularly imprinted polymer surface microenvironment for selective stationary phase–exemplary of S-pramipexole …
M Sobiech, J Giebułtowicz, M Woźnica, I Jaworski… - Microchemical …, 2022 - Elsevier
In this paper, the theoretical models of the molecularly imprinted polymer surface
microenvironment were investigated. S-Pramipexole was used as a model drug and its …
microenvironment were investigated. S-Pramipexole was used as a model drug and its …
Application of co-amorphous technology for improving the physicochemical properties of amorphous formulations
R Mizoguchi, H Waraya, Y Hirakura - Molecular pharmaceutics, 2019 - ACS Publications
Co-amorphous technology was recently introduced to stabilize drugs in the amorphous state
for drug development. We examined the predictability of the formation of co-amorphous …
for drug development. We examined the predictability of the formation of co-amorphous …
Matrix systems for oral drug delivery: Formulations and drug release
In this current article matrix formulations for oral drug delivery are reviewed. Conventional
dosage forms and novel applications such as 3D printed matrices and aerogel matrices are …
dosage forms and novel applications such as 3D printed matrices and aerogel matrices are …
Nanoparticles of N-Vinylpyrrolidone Amphiphilic Copolymers and Pheophorbide a as Promising Photosensitizers for Photodynamic Therapy: Design, Properties and …
AY Rybkin, SV Kurmaz, EA Urakova, NV Filatova… - Pharmaceutics, 2023 - mdpi.com
A series of nanoparticles (NPs) with a hydrodynamic radius from 20 to 100 nm in PBS was
developed over the solubilization of hydrophobic dye methyl pheophorbide a (chlorin e6 …
developed over the solubilization of hydrophobic dye methyl pheophorbide a (chlorin e6 …
A sustainable approach for the degradation kinetics study and stability assay of the SARS-CoV-2 oral antiviral drug Molnupiravir
Molnupiravir (MPV) is the first direct-acting oral antiviral drug that effectively decreases
nasopharyngeal infections with SARS-CoV-2 virus. The stability of MPV was tested by …
nasopharyngeal infections with SARS-CoV-2 virus. The stability of MPV was tested by …