Patient-derived xenograft (PDX) models, in which tumor tissues from patients are implanted
into immunocompromised or humanized mice, have shown superiority in recapitulating the …

Leukemia is a malignancy of the hematopoietic system, and as its pathogenesis has
become better understood, three generations of tyrosine kinase inhibitors (TKIs) have been …

The intestinal epithelium acts as a physical barrier that separates the intestinal microbiota
from the host and is critical for preserving intestinal homeostasis. The barrier is formed by …

Colorectal cancer (CRC), despite the advances in screening and surveillance, remains the
second most common cause of cancer death worldwide. The biological inadequacy of pre …

Precision oncology relies on detailed molecular analysis of how diverse tumours respond to
various therapies, with the aim to optimize treatment outcomes for individual patients. Patient …

Colorectal cancer is the third most common cancer in the United States and responsible for
over 50,000 deaths each year. Therapeutic options for advanced colorectal cancer are …

Aim: This study was designed to investigate the anticancer efficacy of the organic leaf
extracts of the plant, Plectranthus vettiveroides (P. vettiveroides), and to analyze the …

Abstract Patient‐Derived Organoids (PDO) and Xenografts (PDX) are the current gold
standards for patient‐derived models of cancer (PDMC). Nevertheless, how patient tumor …

Simple Summary Osteosarcoma is a rare bone cancer that occurs primarily in children. The
discovery of new treatments for osteosarcoma and other rare cancer types has been …

In the field of precision medicine, therapy is optimized individually for each patient,
enhancing efficacy while reducing side effects. This involves the identification of promising …