Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Glycoproteomics, or characterizing glycosylation events at a proteome scale, has seen rapid
advances in methods for analyzing glycopeptides by tandem mass spectrometry in recent …

Peptide identification in liquid chromatography-tandem mass spectrometry (LC-MS/MS)
experiments relies on computational algorithms for matching acquired MS/MS spectra …

Post-translational modifications are an area of great interest in mass spectrometry-based
proteomics, with a surge in methods to detect them in recent years. However, post …

Here we present GlycanFinder, a database search and de novo sequencing tool for the
analysis of intact glycopeptides from mass spectrometry data. GlycanFinder integrates …

Accurate glycopeptide identification in mass spectrometry-based glycoproteomics is a
challenging problem at scale. Recent innovation has been made in increasing the scope …

At mammalian neuronal synapses, synaptic vesicle (SV) glycoproteins are essential for
robust neurotransmission. Asparagine (N)-linked glycosylation is required for delivery of the …

Precision map** of site-specific glycans using mass spectrometry is vital in
glycoproteomics. However, the diversity of glycan compositions across species often …

Recent interest in targeted therapies has been sparked by the study of MHC-associated
peptides (MAPs) that undergo post-translational modifications (PTMs), particularly …

Protein glycosylation, a post-translational modification of proteins by glycans, plays an
important role in numerous physiological and pathological cellular functions …