Lyophilization of nanoparticle (NP) suspensions is a promising technology to improve
stability, especially during long-term storage, and offers new routes of administration in solid …

Drug nanoparticles embedded in a dispersant matrix as a secondary phase, ie, drug-laden
nanocomposites, offer a versatile delivery platform for enhancing the dissolution rate and …

Advancements in in silico techniques of lead molecule selection have resulted in the failure
of around 70% of new chemical entities (NCEs). Some of these molecules are getting …

This review was devoted to the technology and approach for improving nanosuspensions
stability in drug delivery to retrieve the state-of-the-art nanosuspensions. The main content of …

Particle size reduction can be used for enhancing the dissolution of poorly water-soluble
drugs in order to enhance bioavailability. In nanosuspensions, the particle size of the drug is …

To improve its poor aqueous solubility and stability, the potential chemopreventive agent
quercetin was encapsulated in freeze-dried polymeric micelles by a thin film hydration and …

Although heat is generated during the wet stirred media milling of drug suspensions, leading
to notable temperature rise, a comprehensive analysis of heat generation does not exist …

Cannabidiol (CBD) has poor water solubility and is subjected to extensive first-pass
metabolism. These absorption obstacles are responsible for low and variable oral …

The aim of the present investigation was to enhance the oral bioavailability of olmesartan
medoxomil by improving its solubility and dissolution rate by preparing nanosuspension …

The efficient design of nanocarriers is a major challenge and must be correlated with the
route of administration. Intranasal route is studied for local, systemic or cerebral treatments …