Waves in embryonic development

S Di Talia, M Vergassola - Annual review of biophysics, 2022 - annualreviews.org
Embryonic development hinges on effective coordination of molecular events across space
and time. Waves have recently emerged as constituting an ubiquitous mechanism that …

Chemical waves in cell and developmental biology

VE Deneke, S Di Talia - Journal of Cell Biology, 2018 - rupress.org
Many biological events, such as the propagation of nerve impulses, the synchronized cell
cycles of early embryogenesis, and collective cell migration, must be coordinated with …

Scaling laws governing stochastic growth and division of single bacterial cells

S Iyer-Biswas, CS Wright, JT Henry… - Proceedings of the …, 2014 - National Acad Sciences
Uncovering the quantitative laws that govern the growth and division of single cells remains
a major challenge. Using a unique combination of technologies that yields unprecedented …

Waves of Cdk1 activity in S phase synchronize the cell cycle in Drosophila embryos

VE Deneke, A Melbinger, M Vergassola, S Di Talia - Developmental cell, 2016 - cell.com
Embryos of most metazoans undergo rapid and synchronous cell cycles following
fertilization. While diffusion is too slow for synchronization of mitosis across large spatial …

Emergence of collective modes and tri-dimensional structures from epithelial confinement

M Deforet, V Hakim, HG Yevick, G Duclos… - Nature …, 2014 - nature.com
Many in vivo processes, including morphogenesis or tumour maturation, involve small
populations of cells within a spatially restricted region. However, the basic mechanisms …

Mitotic waves in the early embryogenesis of Drosophila: Bistability traded for speed

M Vergassola, VE Deneke… - Proceedings of the …, 2018 - National Acad Sciences
Early embryogenesis of most metazoans is characterized by rapid and synchronous
cleavage divisions. Chemical waves of Cdk1 activity were previously shown to spread …

Manipulating the nature of embryonic mitotic waves

L Hayden, W Hur, M Vergassola, S Di Talia - Current Biology, 2022 - cell.com
Early embryogenesis is characterized by rapid and synchronous cleavage divisions, which
are often controlled by wave-like patterns of Cdk1 activity. Two mechanisms have been …

Mechanotransduction's impact on animal development, evolution, and tumorigenesis

ME Fernandez-Sanchez, T Brunet… - Annual review of cell …, 2015 - annualreviews.org
Mechanotransduction translates mechanical signals into biochemical signals. It is based on
the soft-matter properties of biomolecules or membranes that deform in response to …

[ΒΙΒΛΙΟ][B] Embryogenesis explained

NK Gordon, R Gordon - 2016 - books.google.com
The greatest mystery of life is how a single fertilized egg develops into a fully functioning,
sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory …

Cytoskeletal mechanics and dynamics in the Drosophila syncytial embryo

Z Lv, J De-Carvalho, IA Telley… - Journal of Cell …, 2021 - journals.biologists.com
Cell and tissue functions rely on the genetic programmes and cascades of biochemical
signals. It has become evident during the past decade that the physical properties of soft …