MP-RNA: Unleashing Multi-species RNA Foundation Model via Calibrated Secondary Structure Prediction
RNA foundation models (FMs) have been extensively used to interpret genomic sequences
and address a wide range of in-silico genomic tasks. However, current RNA FMs often …
and address a wide range of in-silico genomic tasks. However, current RNA FMs often …
OmniGenome: Aligning RNA Sequences with Secondary Structures in Genomic Foundation Models
The alignment between RNA sequences and structures in foundation models (FMs) has yet
to be thoroughly investigated. Existing FMs have struggled to establish sequence-structure …
to be thoroughly investigated. Existing FMs have struggled to establish sequence-structure …
KinPFN: Bayesian Approximation of RNA Folding Kinetics using Prior-Data Fitted Networks
RNA is a dynamic biomolecule crucial for cellular regulation, with its function largely
determined by its folding into complex structures, while misfolding can lead to multifaceted …
determined by its folding into complex structures, while misfolding can lead to multifaceted …
RNACG: A Universal RNA Sequence Conditional Generation model based on Flow-Matching
L Gao, ZJ Lu - arxiv preprint arxiv:2407.19838, 2024 - arxiv.org
RNA plays a crucial role in diverse life processes. In contrast to the rapid advancement of
protein design methods, the work related to RNA is more demanding. Most current RNA …
protein design methods, the work related to RNA is more demanding. Most current RNA …
Old dog, new tricks: Exact seeding strategy improves RNA design performances
The Inverse Folding problem involves identifying RNA sequences that adopt a target
structure with respect to free-energy minimization, ie preferential to all alternative structures …
structure with respect to free-energy minimization, ie preferential to all alternative structures …
[PDF][PDF] Secondary-Structure-Informed RNA Inverse Design via Relational Graph Neural Networks
A Manzourolajdad, M Mohebbi - 2024 - preprints.org
RNA inverse design is an essential part of many RNA therapeutics strategies. To date, there
have been great advances in the computationally-driven RNA design. Current machine …
have been great advances in the computationally-driven RNA design. Current machine …