Cancer diseases are widely recognised as an important medical problem and killing millions
of people in a year. Chemotherapeutic drugs are successful against cancer in many cases …

The human T cell leukemic/lymphotropic virus type 1 (HTLV-1), discovered several years
ago, is the causative agent for a rapid progressive haematological malignancy, adult T cell …

In the present perspective the advances and real possibilities of 1, 3-dipolar cycloadditions
as key steps in the total synthesis of virus inhibitors are described. Azides, nitrones, and …

A novel organocatalytic formal [3+ 2] cycloaddition reaction with in situ generation of N-
carbamoyl nitrones is presented. For the first time, N-Boc-and N-Cbz-protected …

The effects of an extract from Citrus bergamia (BSext) and those of two products purified
from the same extract, that is, nomilin and limonin, and reference compounds, towards HTLV …

The fluorine atom plays an important role in medicinal chemistry because fluorine
substitution has a strong impact on the physical, chemical, and biological properties of …

A new family of polystyrene‐supported cis‐4‐hydroxydiphenylprolinol silyl ethers has been
prepared, and the resulting polymers have been evaluated as organocatalysts to promote …

Five to ten million individuals are infected by Human T-cell Leukemia Virus type 1 (HTLV-1).
HTLV-1 is transmitted through prolonged breast-feeding, by sexual contacts and by …

The present review contains a representative sampling from the last 10 years on the
synthesis of biologically interesting compounds, prepared by the use of the 1, 3-dipolar …

A spiro‐pyrrolidine‐catalyzed tandem aza‐1, 4‐addition/hemi‐acetalization reaction was
developed with excellent enantioselectivity (12 examples of≥ 99% ee), and several …