[HTML][HTML] Calcium phosphate-based biomaterials for bone repair

X Hou, L Zhang, Z Zhou, X Luo, T Wang… - Journal of functional …, 2022‏ - mdpi.com
Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G **… - Chemical …, 2017‏ - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Engineering Large‐Scale Self‐Mineralizing Bone Organoids with Bone Matrix‐Inspired Hydroxyapatite Hybrid Bioinks

J Wang, Y Wu, G Li, F Zhou, X Wu, M Wang… - Advanced …, 2024‏ - Wiley Online Library
Addressing large bone defects remains a significant challenge owing to the inherent
limitations in self‐healing capabilities, resulting in prolonged recovery and suboptimal …

A Janus‐ROS Healing System Promoting Infectious Bone Regeneration via Sono‐Epigenetic Modulation

L Ma, Y Cheng, X Feng, X Zhang, J Lei… - Advanced …, 2024‏ - Wiley Online Library
Elimination of bacterial infections and simultaneously promoting osteogenic differentiation
are highly required for infectious bone diseases. Massive reactive oxygen species (ROS) …

Bone physiology as inspiration for tissue regenerative therapies

D Lopes, C Martins-Cruz, MB Oliveira, JF Mano - Biomaterials, 2018‏ - Elsevier
The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

The roles of signaling pathways in bone repair and regeneration

M Majidinia, A Sadeghpour… - Journal of cellular …, 2018‏ - Wiley Online Library
Regenerative medicine has sparked interest in potential strategies for bone repair. Bone
defects are widespread and could be caused by trauma, congenital malformations …

Effect of microporosity on scaffolds for bone tissue engineering

K Zhang, Y Fan, N Dunne, X Li - Regenerative biomaterials, 2018‏ - academic.oup.com
Microporosity has a critical role in improving the osteogenesis of scaffolds for bone tissue
engineering. Although the exact mechanism, by which it promotes new bone formation, is …

Piezocatalytically-induced controllable mineralization scaffold with bone-like microenvironment to achieve endogenous bone regeneration

X Cui, L Xu, Y Shan, J Li, J Ji, E Wang, B Zhang, X Wen… - Science Bulletin, 2024‏ - Elsevier
Orderly hierarchical structure with balanced mechanical, chemical, and electrical properties
is the basis of the natural bone microenvironment. Inspired by nature, we developed a …

Materials as stem cell regulators

WL Murphy, TC McDevitt, AJ Engler - Nature materials, 2014‏ - nature.com
The stem cell/material interface is a complex, dynamic microenvironment in which the cell
and the material cooperatively dictate one another's fate: the cell by remodelling its …

[HTML][HTML] Biomaterial-induced pathway modulation for bone regeneration

S Vermeulen, ZT Birgani, P Habibovic - Biomaterials, 2022‏ - Elsevier
Embryogenic developmental processes involve a tightly controlled regulation between
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …