Parkinson's disease is the second most common neurodegenerative disease and its
prevalence has been projected to double over the next 30 years. An accurate diagnosis of …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …

Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

A major challenge in Parkinson's disease is the variability in symptoms and rates of
progression, underpinned by heterogeneity of pathological processes. Biomarkers are …

In the CNS, iron in several proteins is involved in many important processes such as oxygen
transportation, oxidative phosphorylation, myelin production, and the synthesis and …

In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

Susceptibility‐weighted imaging (SWI) is a magnetic resonance imaging (MRI) technique
that enhances image contrast by using the susceptibility differences between tissues. It is …

Cerebral microbleeds (CMBs), also referred to as microhemorrhages, appear on magnetic
resonance (MR) images as hypointense foci notably at T2*-weighted or susceptibility …

During the last five years ultra-high-field magnetic resonance imaging (MRI) has enabled an
unprecedented view of living human brain. Brain tissue contrast in most MRI sequences is …