Aging is a progressive and irreversible pathophysiological process that manifests as the
decline in tissue and cellular functions, along with a significant increase in the risk of various …

Patients with obesity have a high prevalence of nonalcoholic fatty liver disease (NAFLD),
representing a spectrum of simple steatosis to nonalcoholic steatohepatitis (NASH), without …

Humans have lived in a dynamic environment fraught with potential dangers for thousands
of years. While fear and stress were crucial for the survival of our ancestors, today, they are …

Growth hormone (GH) is critical for achieving normal structural growth. In addition, GH plays
an important role in regulating metabolic function. GH acts through its GH receptor (GHR) to …

Dysfunctions in growth hormone (GH) secretion increase the prevalence of anxiety and
other neuropsychiatric diseases. GH receptor (GHR) signaling in the amygdala has been …

Exercise has received considerable attention because of its importance not just in regulating
physiological function, but also in ameliorating multiple pathological processes. Among …

High neonatal growth hormone (GH) secretion has been described in several species.
However, the neuroendocrine mechanisms behind this surge remain unknown. Thus, the …

Hypophysiotropic somatostatin (SST) neurons in the periventricular hypothalamic area
express growth hormone (GH) receptor (GHR) and are frequently considered as the key …

Growth hormone (GH) secretion is controlled by short and long negative feedback loops. In
this regard, both GH (short-loop feedback) and insulin-like growth factor 1 (IGF-1; long-loop …

As obesity rates have risen around the world, so to have pregnancies complicated by
maternal obesity. Obesity during pregnancy is not only associated with negative health …