The increase in the human population in addition to the massive demand for protein of
animal origin forced the authorities to seek for additional sources of feed supplies …

Covering: 2005 to August, 2023 Polyamine-containing natural products (NPs) have been
isolated from a wide range of terrestrial and marine organisms and most of them exhibit …

Nonribosomal peptides and polyketides are a diverse group of natural products with
complex chemical structures and enormous pharmaceutical potential. They are synthesized …

Covering: July 2012 to June 2015. Previous review: Nat. Prod. Rep., 2013, 30, 869–915 The
structurally diverse imidazole-, oxazole-, and thiazole-containing secondary metabolites are …

Nonribosomal peptides (NRP) are crucial molecular mediators in microbial ecology and
provide indispensable drugs. Nevertheless, the evolution of the flexible biosynthetic …

Bacterial genomes are rife with orphan biosynthetic gene clusters (BGCs) associated with
secondary metabolism of unrealized natural product molecules. Often up to a tenth of the …

Nonribosomal peptide synthetases (NRPSs) are a family of multidomain, multimodule
enzymes that synthesize structurally and functionally diverse peptides, many of which are of …

The broad bioactivities of nonribosomal peptides rely on increasing structural diversity.
Genome mining of the Burkholderiales strain Schlegelella brevitalea DSM 7029 leads to the …

In this study, we performed a detailed characterization of the siderophore metabolome, or
“chelome,” of the agriculturally important and widely studied model organism Azotobacter …

Using automated genome analysis tools, it is often unclear to what degree genetic variability
in homologous biosynthetic pathways relates to structural variation. This hampers strain …