Role of microRNA-34a in blood–brain barrier permeability and mitochondrial function in ischemic stroke

CT Payne, S Tabassum, S Wu, H Hu… - Frontiers in Cellular …, 2023 - frontiersin.org
Over the past decade, there has been an uptick in the number of studies conducting
research on the role of microRNA (miRNA) molecules in stroke. Among these molecules …

[HTML][HTML] The emerging role of pericyte-derived extracellular vesicles in vascular and neurological health

K Sharma, Y Zhang, KR Paudel, A Kachelmeier… - Cells, 2022 - mdpi.com
Pericytes (PCs), as a central component of the neurovascular unit, contribute to the
regenerative potential of the central nervous system (CNS) and peripheral nervous system …

[HTML][HTML] circRNAs as epigenetic regulators of integrity in blood–brain barrier architecture: mechanisms and therapeutic strategies in multiple sclerosis

E D'Aversa, F Salvatori, M Vaccarezza, B Antonica… - Cells, 2024 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease leading to
progressive demyelination and neuronal loss, with extensive neurological symptoms. As …

Implementation of blood-brain barrier on microfluidic chip: Recent advance and future prospects

W Bi, S Cai, T Lei, L Wang - Ageing Research Reviews, 2023 - Elsevier
The complex structure of the blood-brain barrier (BBB) hinders its modeling and the
treatment of brain diseases. The microfluidic technology promotes the development of BBB …

[HTML][HTML] Exosomal MicroRNAs in Alzheimer's Disease: Unveiling Their Role and Pioneering Tools for Diagnosis and Treatment

A Alhenaky, S Alhazmi, SH Alamri… - Journal of Clinical …, 2024 - mdpi.com
Alzheimer's disease (AD) is a common neurodegenerative disorder that presents a
significant health concern, often leading to substantial cognitive decline among older adults …

Circulating plasma miR-23b-3p as a biomarker target for idiopathic Parkinson's disease: comparison with small extracellular vesicle miRNA

S Rai, PS Bharti, R Singh, S Rastogi, K Rani… - Frontiers in …, 2023 - frontiersin.org
Background Parkinson's disease (PD) is an increasingly common neurodegenerative
condition, which causes movement dysfunction and a broad range of non-motor symptoms …

[HTML][HTML] New insights of miRNA molecular mechanisms in breast cancer brain metastasis and therapeutic targets

BM Hussen, KH Abdullah, SR Abdullah… - Non-coding RNA …, 2023 - Elsevier
Brain metastases in breast cancer (BC) patients are often associated with a poor prognosis.
Recent studies have uncovered the critical roles of miRNAs in the initiation and progression …

Potential pharmacological target of tight junctions to improve the BBB permeability in neonatal Hypoxic-Ischemic encephalopathy Diseases

AA Paz, A González-Candia - Biochemical Pharmacology, 2023 - Elsevier
Neonatal encephalopathy (NE) is a pathological condition that describes a neurocognitive
malfunction in the newborn that arises from fetal, peripartum, or intrapartum events of …

[HTML][HTML] A microfluidic in vitro three-dimensional dynamic model of the blood–brain barrier to study the transmigration of immune cells

M Meena, R Vandormael, M De Laere, I Pintelon… - Brain sciences, 2022 - mdpi.com
To study the biodistribution of new chemical and biological entities, an in vitro model of the
blood–brain barrier (BBB) may become an essential tool during early phases of drug …

MicroRNA expression profile of human umbilical vein endothelial cells in response to coxsackievirus A10 infection reveals a potential role of miR-143-3p in …

Y Hu, F Cui, S Wang, C Liu, S Zhang… - Frontiers in Cellular …, 2023 - frontiersin.org
Coxsackievirus A10 (CV-A10) has been one of the main etiologies of hand, foot, and mouth
disease (HFMD) epidemics in recent years and can cause mild to severe illness and even …