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CRISPR/Cas9 therapeutics: progress and prospects
T Li, Y Yang, H Qi, W Cui, L Zhang, X Fu, X He… - Signal transduction and …, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …
Stimuli-activatable nanomedicine meets cancer theranostics
Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics.
Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine …
Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine …
Metal–organic frameworks for biological applications
Metal–organic frameworks (MOFs) have emerged as exciting potential new candidates for
application across nanomedicine, with the first example now in a phase II human clinical …
application across nanomedicine, with the first example now in a phase II human clinical …
A bimetallic nanoplatform for STING activation and CRISPR/Cas mediated depletion of the methionine transporter in cancer cells restores anti-tumor immune …
Y Huang, G Qin, TT Cui, C Zhao, J Ren, X Qu - Nature Communications, 2023 - nature.com
Lack of sufficient cytotoxic T lymphocytes (CD8+ T cells) infiltration and dysfunctional state of
CD8+ T cells are considered enormous obstacles to antitumor immunity. Herein, we …
CD8+ T cells are considered enormous obstacles to antitumor immunity. Herein, we …
Metal–organic frameworks for drug delivery: a design perspective
The use of metal–organic frameworks (MOFs) in biomedical applications has greatly
expanded over the past decade due to the precision tunability, high surface areas, and high …
expanded over the past decade due to the precision tunability, high surface areas, and high …
Metal–organic framework-based enzyme biocomposites
Because of their efficiency, selectivity, and environmental sustainability, there are significant
opportunities for enzymes in chemical synthesis and biotechnology. However, as the three …
opportunities for enzymes in chemical synthesis and biotechnology. However, as the three …
The uptake of metal–organic frameworks: a journey into the cell
The application of metal–organic frameworks (MOFs) in drug delivery has advanced rapidly
over the past decade, showing huge progress in the development of novel systems …
over the past decade, showing huge progress in the development of novel systems …
Metal–organic framework nanocarriers for drug delivery in biomedical applications
Investigation of metal–organic frameworks (MOFs) for biomedical applications has attracted
much attention in recent years. MOFs are regarded as a promising class of nanocarriers for …
much attention in recent years. MOFs are regarded as a promising class of nanocarriers for …
Stimuli-responsive drug delivery systems triggered by intracellular or subcellular microenvironments
T Sun, C Jiang - Advanced drug delivery reviews, 2023 - Elsevier
Drug delivery systems (DDS) triggered by local microenvironment represents the state-of-art
of nanomedicine design, where the triggering hallmarks at intracellular and subcellular …
of nanomedicine design, where the triggering hallmarks at intracellular and subcellular …
Metal–organic framework-functionalized paper-based electrochemical biosensor for ultrasensitive exosome assay
X Liu, X Gao, L Yang, Y Zhao, F Li - Analytical chemistry, 2021 - ACS Publications
The exosome has emerged as a promising noninvasive biomarker for the early diagnosis of
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …