Adenosine: Synthetic methods of its derivatives and antitumor activity

FZ Valdés, VZ Luna, BR Arévalo… - Mini Reviews in …, 2018 - ingentaconnect.com
Since 1929, several researchers have conducted studies in relation to the nucleoside of
adenosine (1) mainly distribution identifying, characterizing their biological importance and …

Current Strategies on the Enantioselective Synthesis of Modified Nucleosides

SK Mondal, B Mahto, S Pal, G Chandra - Synlett, 2024 - thieme-connect.com
The isolation of two carbocyclic nucleosides, viz., neplanocin A and aristeromycin, from
natural sources, triggered a revolution in the scientific community, leading to the …

Current Strategies on the Enantioselective Synthesis of Modified Nucleosides

S Pal, G Chandra, SK Mondal, B Mahto - Synlett, 2023 - thieme-connect.com
After the isolation of two carbocyclic nucleosides, viz Neplanocin A and Aristeromycin, from
natural sources, a revolution came into the scientific community to develop more versatile …

Intramolecular Hydrogen Bonding in N6-Substituted 2-Chloroadenosines: Evidence from NMR Spectroscopy

MY Berzina, BZ Eletskaya, AL Kayushin… - International Journal of …, 2023 - mdpi.com
Two forms were found in the NMR spectra of N6-substituted 2-chloroadenosines. The
proportion of the mini-form was 11–32% of the main form. It was characterized by a separate …

Synthesis and cytotoxic evaluation of apioarabinofuranosyl pyrimidines

B Sivakrishna, S Islam, MK Santra… - Drug Development …, 2020 - Wiley Online Library
In view of the potent anticancer activity of the d‐arabino‐configured cytosine nucleoside (ara‐
C), apioarabinofuranosyl pyrimidine nucleosides were designed and synthesized from d …

Synthesis and anticancer properties of novel truncated carbocyclic nucleoside analogues

B Sivakrishna, S Islam, A Panda… - Anti-Cancer Agents …, 2018 - ingentaconnect.com
Background: Modified nucleosides established a prime role as therapeutic drugs. Objective:
Design and synthesis of novel truncated carbocyclic nucleoside with modified nucleobases …

Two New Adenosine Derivatives and their Antiproliferative Properties: An In Vitro Evaluation

F Valdés, B Arévalo, M Gutiérrez… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Background: Adenosine is a natural nucleoside present in a variety of organs and tissues,
where it acts as a modulator of diverse physiological and pathophysiological processes …