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Testicular cancer
Testicular cancer is the most common malignancy among men between 14 and 44 years of
age, and its incidence has risen over the past two decades in Western countries. Both …
age, and its incidence has risen over the past two decades in Western countries. Both …
Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …
in their populations due to persistently low total fertility rates (TFR) below replacement level …
Integrated molecular characterization of testicular germ cell tumors
We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays
of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited …
of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited …
HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease
More than 90% of common variants associated with complex traits do not affect proteins
directly, but instead the circuits that control gene expression. This has increased the urgency …
directly, but instead the circuits that control gene expression. This has increased the urgency …
Testicular germ cell tumours
E Rajpert-De Meyts, KA McGlynn, K Okamoto… - The Lancet, 2016 - thelancet.com
Testicular germ cell tumours are at the crossroads of developmental and neoplastic
processes. Their cause has not been fully elucidated but differences in incidences suggest …
processes. Their cause has not been fully elucidated but differences in incidences suggest …
Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses
XCMS Online (xcmsonline. scripps. edu) is a cloud-based informatic platform designed to
process and visualize mass-spectrometry-based, untargeted metabolomic data. Initially, the …
process and visualize mass-spectrometry-based, untargeted metabolomic data. Initially, the …
Gastroenteropancreatic neuroendocrine tumours: the current incidence and staging based on the WHO and European Neuroendocrine Tumour Society classification …
MB Niederle, M Hackl, K Kaserer… - Endocrine-related …, 2010 - erc.bioscientifica.com
Germline inactivating mutations of isoform 4 of phosphodiesterase (PDE) 11A (coded by the
PDE11A gene) have been associated with familial adrenocortical tumors and familial …
PDE11A gene) have been associated with familial adrenocortical tumors and familial …
Testicular germ cell tumor: a comprehensive review
A Batool, N Karimi, XN Wu, SR Chen, YX Liu - Cellular and Molecular Life …, 2019 - Springer
Testicular tumors are the most common tumors in adolescent and young men and germ cell
tumors (TGCTs) account for most of all testicular cancers. Increasing incidence of TGCTs …
tumors (TGCTs) account for most of all testicular cancers. Increasing incidence of TGCTs …
International variations and trends in testicular cancer incidence and mortality
Context Testicular cancer (TC) is the most common cancer in men aged 15–44 yr in many
countries that score high or very high on the Human Development Index (HDI). Despite the …
countries that score high or very high on the Human Development Index (HDI). Despite the …
[HTML][HTML] Human germ cell tumors are developmental cancers: impact of epigenetics on pathobiology and clinic
Current (high throughput omics-based) data support the model that human (malignant) germ
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …